Published in:
01-12-2020 | Voriconazole | Hot Topics
Cladorrhinum Bulbillosum Keratitis: Unraveling an Unusual Infection
Published in: Current Fungal Infection Reports | Issue 4/2020
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Purpose of Review
To analyze the presentation and outcome of keratitis due to Cladorrhinum bulbillosum which is a rare species of fungus sparsely reported in literature.
Recent Findings
In the genus Cladorrhinum, C. bulbillosum is the only reported pathogenic species causing keratitis. There have been only 3 reported cases in the literature thus far.
Summary
Ours is the first reported case series of 4 patients with keratitis caused by the rare dematiaceous organism Cladorrhinum bulbillosum. This keratomycosis can be variably pigmented clinically. Even though it has a typical morphological appearance on microscopy, molecular testing in the form of PCR and DNA sequencing aids in the diagnosis. Keratomycosis caused by this organism can have a protracted clinical course but can be managed medically alone. The need for surgical intervention may arise only in non-responsive cases where there are coexistent ocular or systemic morbidities.