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Journal of Cardiovascular Translational Research

Published in:

01-10-2018 | Review Paper

Stem Cell Homing: a Potential Therapeutic Strategy Unproven for Treatment of Myocardial Injury

Authors: Zhonghao Tao, Shihua Tan, Wen Chen, Xin Chen

Published in: Journal of Cardiovascular Translational Research | Issue 5/2018

Abstract

Despite advances in the prevention and therapeutic modalities of ischemic heart disease, morbidity and mortality post-infarction heart failure remain big challenges in modern society. Stem cell therapy is emerging as a promising therapeutic strategy. Stem cell homing, the ability of stem cells to find their destination, is receiving more attention. Identification of specific cues and understanding the signaling pathways that direct stem cells to targeted destination will improve stem cell homing efficiency. This review discusses the cellular and molecular mechanism of stem cell homing at length in the light of literature and analyzes the problem and considerations of this approach as a treatment strategy for the treatment of ischemic heart disease clinically.

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Title: Stem Cell Homing: a Potential Therapeutic Strategy Unproven for Treatment of Myocardial Injury
Authors: Zhonghao Tao
Shihua Tan
Wen Chen
Xin Chen
Publication date: 01-10-2018
Publisher: Springer US
Published in: Journal of Cardiovascular Translational Research / Issue 5/2018
Print ISSN: 1937-5387
Electronic ISSN: 1937-5395
DOI: https://doi.org/10.1007/s12265-018-9823-z

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Stem Cell Homing: a Potential Therapeutic Strategy Unproven for Treatment of Myocardial Injury

Abstract

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Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

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Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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Other articles of this Issue 5/2018

The Application of Induced Pluripotent Stem Cells in Cardiac Disease Modeling and Drug Testing

Endothelial Progenitor Cells in Heart Failure: an Authentic Expectation for Potential Future Use and a Lack of Universal Definition

Exosome-Derived Dystrophin from Allograft Myogenic Progenitors Improves Cardiac Function in Duchenne Muscular Dystrophic Mice

Maturation of Pluripotent Stem Cell-Derived Cardiomyocytes: a Critical Step for Drug Development and Cell Therapy

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Transplantation of Cardiac Mesenchymal Stem Cell-Derived Exosomes Promotes Repair in Ischemic Myocardium

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Year in Review: Heart failure and cardiomyopathies

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