Published in:
01-06-2019 | Multiple Myeloma | Guide Line
JSH practical guidelines for hematological malignancies, 2018: III. Myeloma-2. Related disorders of multiple myeloma
Authors:
Shinsuke Iida, Chihiro Shimazaki, Masahiro Abe, Chiaki Nakaseko
Published in:
International Journal of Hematology
|
Issue 6/2019
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Excerpt
In the International Myeloma Working Group (IMWG) classification, solitary plasmacytomas of bone or soft tissue are defined as meeting the four criteria of (1) biopsy-proven plasmacytoma of bone or soft tissue with evidence of clonal plasma cells, (2) normal bone marrow with no evidence of clonal plasma cells, (3) normal bone X-ray and MRI (or CT) of spine and pelvis (except for the solitary plasmacytoma lesion), and (4) absence of end-organ damage such as hypercalcemia, renal insufficiency, anemia, or bone lesions (CRAB) [1]. Solitary plasmacytomas of bone or soft tissue with minimal marrow involvement are further defined as meeting the four criteria of (1) biopsy-proven plasmacytoma of bone or soft tissue with evidence of clonal plasma cells, (2) clonal bone marrow plasma cells < 10%, (3) normal bone X-ray and MRI (or CT) of spine and pelvis (except for the solitary plasmacytoma lesion), and (4) absence of CRAB [1]. …
