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01-07-2008 | Case Report

Nocardia exalbida brain abscess in a patient with follicular lymphoma

Authors: Makiko Ono, Yukio Kobayashi, Tsuyoshi Shibata, Dai Maruyama, Sung-Won Kim, Takashi Watanabe, Yuzuru Mikami, Kensei Tobinai

Published in: International Journal of Hematology | Issue 1/2008

Abstract

Nocardial brain abscess is a rare but severe complication in patients with malignancy. Nocardia exalbida was isolated in Japan and characterized within the genus Nocardia. We present the first report of N. exalbida brain abscess in a 63-year-old male patient with follicular lymphoma. He developed abnormal neurological findings during follicular lymphoma treatment, brain CT revealed ring-enhancing, multiloculated lesions, and N. exalbida was detected by aspiration of the lesion. He was successfully treated with trimethoprime–sulfamethoxazole (TMP–SMX) and meropenem without craniotomy or repeat aspirations. It should be noted that such an infection can occur in patients treated with conventional chemotherapy against malignant lymphoma.

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Title: Nocardia exalbida brain abscess in a patient with follicular lymphoma
Authors: Makiko Ono
Yukio Kobayashi
Tsuyoshi Shibata
Dai Maruyama
Sung-Won Kim
Takashi Watanabe
Yuzuru Mikami
Kensei Tobinai
Publication date: 01-07-2008
Publisher: Springer Japan
Published in: International Journal of Hematology / Issue 1/2008
Print ISSN: 0925-5710
Electronic ISSN: 1865-3774
DOI: https://doi.org/10.1007/s12185-008-0099-y

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