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Journal of Ocular Biology, Diseases, and Informatics
Published in: Journal of Ocular Biology, Diseases, and Informatics 1/2008

Open Access 01-03-2008

A short-duration dark adaptation protocol for assessment of age-related maculopathy

Authors: Gregory R. Jackson, John G. Edwards

Published in: Journal of Ocular Biology, Diseases, and Informatics | Issue 1/2008

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Abstract

Dark adaptometry may be a useful diagnostic test and clinical trial endpoint for age-related maculopathy (ARM) because impaired night vision is a hallmark of early ARM. A novel dark adaptometer, the AdaptDx, was evaluated for the detection of ARM. The AdaptDx incorporates a 20-minute protocol optimized for the detection of ARM. ARM patients (N = 17) exhibited substantial dark adaptation impairment compared with normal adults (N = 17). The diagnostic sensitivity was 88% and the specificity was 100%. The diagnostic test characteristics of the AdaptDx are similar to previously reported studies using 60- to 120-minute protocols.
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Metadata
Title
A short-duration dark adaptation protocol for assessment of age-related maculopathy
Authors
Gregory R. Jackson
John G. Edwards
Publication date
01-03-2008
Publisher
Humana Press Inc
DOI
https://doi.org/10.1007/s12177-008-9002-6

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