Skip to main content
Top
Published in: Annals of Behavioral Medicine 5/2017

01-10-2017 | Brief Report

The Mediating Role of Meaning in the Association between Stress and Health

Authors: Daryl R. Van Tongeren, PhD, Peter C. Hill, PhD, Neal Krause, PhD, Gail H. Ironson, PhD, Kenneth I. Pargament, PhD

Published in: Annals of Behavioral Medicine | Issue 5/2017

Login to get access

Abstract

Background

Stress is a common feature of life and has routinely been linked with negative health outcomes. However, meaning has been identified as a possible buffer against stress.

Purpose

The purpose of the current study was to examine whether the relationship between stress and health was mediated by meaning in life.

Methods

Drawing from Wave 1 of the Landmark Spirituality and Health Study, a nationally representative sample of adults, participants (N = 1871) reported their level of stress in the past 12 months, current meaning in life, health (measured as minor symptoms, major conditions, and overall health), and provided a blood sample for biomarker of immune system functioning (i.e., presence of Epstein–Barr virus antibodies).

Results

Results revealed an indirect effects model in which stress was inversely associated with meaning. Higher meaning was related to better self-reported health (across minor, major, and overall health measures), which, in turn, was associated with better immune system functioning.

Conclusions

These findings suggest that part of the negative effect of stress on health is accounted for by reduced meaning.
Literature
1.
go back to reference Schneiderman, N, Ironson, G, Siegel, SD. Stress and health: psychological, behavioral, and biological determinants. Ann Rev Clin Psychol. 2005; 1(1): 607–628.CrossRef Schneiderman, N, Ironson, G, Siegel, SD. Stress and health: psychological, behavioral, and biological determinants. Ann Rev Clin Psychol. 2005; 1(1): 607–628.CrossRef
2.
go back to reference Glaser R, Pearson GR, Jones JF, Hillhouse J, et al. Stress-related activation of Epstein–Barr virus. Brain Behav Immun. 1991; 5(2): 219–232.CrossRefPubMed Glaser R, Pearson GR, Jones JF, Hillhouse J, et al. Stress-related activation of Epstein–Barr virus. Brain Behav Immun. 1991; 5(2): 219–232.CrossRefPubMed
3.
go back to reference Glaser R, Rice J, Sheridan J, et al. Stress-related immune suppression: health implications. Brain Behav Immun. 1987; 1(1): 7–20.CrossRefPubMed Glaser R, Rice J, Sheridan J, et al. Stress-related immune suppression: health implications. Brain Behav Immun. 1987; 1(1): 7–20.CrossRefPubMed
4.
go back to reference Thoits PA. Stress and health: major findings and policy implications. J Health Soc Behav. 2010; 51(1 Suppl): S41-S53.CrossRefPubMed Thoits PA. Stress and health: major findings and policy implications. J Health Soc Behav. 2010; 51(1 Suppl): S41-S53.CrossRefPubMed
5.
go back to reference Lazarus RS, Folkman S. Stress, Appraisal, and Coping. New York: Springer Publishing Company; 1984. Lazarus RS, Folkman S. Stress, Appraisal, and Coping. New York: Springer Publishing Company; 1984.
6.
go back to reference Krause N. Evaluating the stress-buffering function of meaning in life among older people. J Aging Health; 2007; 19(5): 792–812.CrossRefPubMed Krause N. Evaluating the stress-buffering function of meaning in life among older people. J Aging Health; 2007; 19(5): 792–812.CrossRefPubMed
7.
go back to reference Frankl, V. Man’s Search for Meaning. Beacon Publishers; 1959. Frankl, V. Man’s Search for Meaning. Beacon Publishers; 1959.
9.
go back to reference Park CL. Making sense of the meaning literature: an integrative review of meaning making and its effects on adjustment to stressful life events. Psychol Bull. 2010; 136(2): 257–301.CrossRefPubMed Park CL. Making sense of the meaning literature: an integrative review of meaning making and its effects on adjustment to stressful life events. Psychol Bull. 2010; 136(2): 257–301.CrossRefPubMed
10.
go back to reference Steger MF, Fitch-Martin AR, Donnelly, J, Rickard KM. Meaning in life and health: proactive health orientation links meaning in life to health variables among American undergraduates. J Happiness Stud. 2015; 16(3): 583–597.CrossRef Steger MF, Fitch-Martin AR, Donnelly, J, Rickard KM. Meaning in life and health: proactive health orientation links meaning in life to health variables among American undergraduates. J Happiness Stud. 2015; 16(3): 583–597.CrossRef
11.
go back to reference Bower JE, Kemeny ME, Taylor SE, Fahey JL. Finding positive meaning and its association with natural killer cell cytotoxicity among participants in a bereavement-related disclosure intervention. Ann Behav Med. 2003; 25(2): 146–155.CrossRefPubMed Bower JE, Kemeny ME, Taylor SE, Fahey JL. Finding positive meaning and its association with natural killer cell cytotoxicity among participants in a bereavement-related disclosure intervention. Ann Behav Med. 2003; 25(2): 146–155.CrossRefPubMed
12.
go back to reference Krause N. Meaning in life and mortality. J Geront: Socl Sci. 2009; 64B(4): 517–527.CrossRef Krause N. Meaning in life and mortality. J Geront: Socl Sci. 2009; 64B(4): 517–527.CrossRef
13.
go back to reference Canada AL, Murphy PE, Fitchett G, Stein K. Re-examining the contributions of faith, meaning, and peace to quality of life: a report from the American Cancer Society’s study of cancer survivors-II (SCS-II). Ann Behav Med. 2016; 50(1): 79–86.CrossRefPubMed Canada AL, Murphy PE, Fitchett G, Stein K. Re-examining the contributions of faith, meaning, and peace to quality of life: a report from the American Cancer Society’s study of cancer survivors-II (SCS-II). Ann Behav Med. 2016; 50(1): 79–86.CrossRefPubMed
14.
go back to reference Jim HSL, Pustejovsky JE, Park, CL, et al. Religion, spirituality, and physical health in cancer patients: a meta-analysis. Cancer. 2015; 121(21): 3760–3768.CrossRefPubMedPubMedCentral Jim HSL, Pustejovsky JE, Park, CL, et al. Religion, spirituality, and physical health in cancer patients: a meta-analysis. Cancer. 2015; 121(21): 3760–3768.CrossRefPubMedPubMedCentral
15.
go back to reference Hood, RW Jr, Hill PC, Williamson WP. The Psychology of Religious Fundamentalism. New York: Guilford Press; 2005. Hood, RW Jr, Hill PC, Williamson WP. The Psychology of Religious Fundamentalism. New York: Guilford Press; 2005.
16.
go back to reference Park CL. Religion as a meaning-making framework in coping with life stress. J Soc Issues. 2005; 61(4): 707–729.CrossRef Park CL. Religion as a meaning-making framework in coping with life stress. J Soc Issues. 2005; 61(4): 707–729.CrossRef
17.
go back to reference Park CL, Edmondson D, Blank, TO. Religious and non-religious pathways to stress-related growth in cancer survivors. App Psychol: Health Well-Being. 2009; 1: 321–335. Park CL, Edmondson D, Blank, TO. Religious and non-religious pathways to stress-related growth in cancer survivors. App Psychol: Health Well-Being. 2009; 1: 321–335.
18.
go back to reference Cohen R, Bavishi C, Rozanski A. Purpose in life and its relationship to all-cause mortality and cardiovascular events: a meta-analysis. Psychosom Med. 2016; 78(2): 122–133.CrossRefPubMed Cohen R, Bavishi C, Rozanski A. Purpose in life and its relationship to all-cause mortality and cardiovascular events: a meta-analysis. Psychosom Med. 2016; 78(2): 122–133.CrossRefPubMed
19.
go back to reference Krause N. Meaning in life and healthy aging. In: Wong, PTP, ed. The Human Quest for Meaning: Theories, Research, and Applications (2nd ed.). New York, NY: Routledge; 2012: 409–432. Krause N. Meaning in life and healthy aging. In: Wong, PTP, ed. The Human Quest for Meaning: Theories, Research, and Applications (2nd ed.). New York, NY: Routledge; 2012: 409–432.
20.
21.
go back to reference Krause N, Hayward RD assessing stability and change in a second-order confirmatory factor model of meaning in life. J Happiness Stud. 2014: 15(2): 237–253.CrossRefPubMed Krause N, Hayward RD assessing stability and change in a second-order confirmatory factor model of meaning in life. J Happiness Stud. 2014: 15(2): 237–253.CrossRefPubMed
22.
go back to reference Magaziner J, Bassett SS, Hebel JR, Cruber-Baldini A. Use of proxies to measure health and functional status in epidemiologic studies of community dwelling women age 65 years and older. Am J Epidemiol. 1996; 143(2): 283–290.CrossRefPubMed Magaziner J, Bassett SS, Hebel JR, Cruber-Baldini A. Use of proxies to measure health and functional status in epidemiologic studies of community dwelling women age 65 years and older. Am J Epidemiol. 1996; 143(2): 283–290.CrossRefPubMed
23.
go back to reference McDade TW, Stallings JF, Angold A. et al. Epstein–Barr virus antibodies in whole blood spots: a minimally invasive method for assessing an aspect of cell-mediated immunity. Psychosom Med. 2000; 62(4): 560–568.CrossRefPubMed McDade TW, Stallings JF, Angold A. et al. Epstein–Barr virus antibodies in whole blood spots: a minimally invasive method for assessing an aspect of cell-mediated immunity. Psychosom Med. 2000; 62(4): 560–568.CrossRefPubMed
24.
go back to reference Hayes AF. Introduction to Mediation, Moderation, and Conditional Process Analysis: A Regression-Based Approach. New York, NY: Guilford Press; 2013. Hayes AF. Introduction to Mediation, Moderation, and Conditional Process Analysis: A Regression-Based Approach. New York, NY: Guilford Press; 2013.
25.
go back to reference Berger PL. The Sacred Canopy: Elements of a Sociological Theory. New York, NY: Doubleday; 1967. Berger PL. The Sacred Canopy: Elements of a Sociological Theory. New York, NY: Doubleday; 1967.
26.
go back to reference Erikson E. Childhood and Society (1st ed.). New York: Norton. 1950 Erikson E. Childhood and Society (1st ed.). New York: Norton. 1950
27.
go back to reference Johnson MA, Mullins P. Moral communities: religious and secular. J Comm Psychol. 1990; 18(2): 153–166.CrossRef Johnson MA, Mullins P. Moral communities: religious and secular. J Comm Psychol. 1990; 18(2): 153–166.CrossRef
Metadata
Title
The Mediating Role of Meaning in the Association between Stress and Health
Authors
Daryl R. Van Tongeren, PhD
Peter C. Hill, PhD
Neal Krause, PhD
Gail H. Ironson, PhD
Kenneth I. Pargament, PhD
Publication date
01-10-2017
Publisher
Springer US
Published in
Annals of Behavioral Medicine / Issue 5/2017
Print ISSN: 0883-6612
Electronic ISSN: 1532-4796
DOI
https://doi.org/10.1007/s12160-017-9899-8

Other articles of this Issue 5/2017

Annals of Behavioral Medicine 5/2017 Go to the issue