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Published in: Annals of Behavioral Medicine 1/2010

01-02-2010 | Original Article

Posttraumatic Stress Disorder, Cardiovascular, and Metabolic Disease: A Review of the Evidence

Authors: Eric A. Dedert, Ph.D., Patrick S. Calhoun, Ph.D., Lana L. Watkins, Ph.D., Andrew Sherwood, Ph.D., Jean C. Beckham, Ph.D.

Published in: Annals of Behavioral Medicine | Issue 1/2010

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Abstract

Background

Posttraumatic stress disorder (PTSD) is a significant risk factor for cardiovascular and metabolic disease.

Purpose

The purpose of the current review is to evaluate the evidence suggesting that PTSD increases cardiovascular and metabolic risk factors, and to identify possible biomarkers and psychosocial characteristics and behavioral variables that are associated with these outcomes.

Methods

A systematic literature search in the period of 2002–2009 for PTSD, cardiovascular disease, and metabolic disease was conducted.

Results

The literature search yielded 78 studies on PTSD and cardiovascular/metabolic disease and biomarkers.

Conclusions

Although the available literature suggests an association of PTSD with cardiovascular disease and biomarkers, further research must consider potential confounds, incorporate longitudinal designs, and conduct careful PTSD assessments in diverse samples to address gaps in the research literature. Research on metabolic disease and biomarkers suggests an association with PTSD, but has not progressed as far as the cardiovascular research.
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Metadata
Title
Posttraumatic Stress Disorder, Cardiovascular, and Metabolic Disease: A Review of the Evidence
Authors
Eric A. Dedert, Ph.D.
Patrick S. Calhoun, Ph.D.
Lana L. Watkins, Ph.D.
Andrew Sherwood, Ph.D.
Jean C. Beckham, Ph.D.
Publication date
01-02-2010
Publisher
Springer-Verlag
Published in
Annals of Behavioral Medicine / Issue 1/2010
Print ISSN: 0883-6612
Electronic ISSN: 1532-4796
DOI
https://doi.org/10.1007/s12160-010-9165-9

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