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01-10-2016 | Original Article

¹⁸F-FDG uptake by rectal cancer is similar in mucinous and nonmucinous histological subtypes

Authors: Dalton A. dos Anjos, Angelita Habr-Gama, Bruna B. Vailati, Cecilia B. Rossi, Adelina E. Coturel, Rodrigo O. Perez, Guilherme P. São Julião, João B. de Sousa, Carlos A. Buchpiguel

Published in: Annals of Nuclear Medicine | Issue 8/2016

Abstract

Purpose

PET/CT has been considered limited for the evaluation of mucinous colorectal tumors due to low ¹⁸F-FDG uptake. The aim of our study was to compare PET/CT variables in mucinous (MC) and nonmucinous (NMC) rectal adenocarcinomas.

Methods

Consecutive patients with cT2-4N0-2M0 rectal cancer included in a prospective clinical trial were reviewed. PET/CT was performed for primary baseline staging. Visual and quantitative analysis included SUVmax and SUVmean, metabolic tumor volume (MTV) and total lesion glycolysis (TLG). PET/CT parameters were compared according to histological subtypes.

Results

Overall, 73 patients were included (18 mucinous and 55 nonmucinous). SUVmax values were similar between MC and NMC (19.7 vs. 16.6; p = 0.5). MTV and TLG values were greater in the MC group (103.9 vs. 54.1; p = 0.007 and 892.5 vs. 358.8; p = 0.020) due to larger tumor volumes of MC.

Conclusions

Metabolic parameters at baseline PET/CT for patients with rectal cancer are similar in mucinous and nonmucinous histological subtypes.

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Title: 18F-FDG uptake by rectal cancer is similar in mucinous and nonmucinous histological subtypes
Authors: Dalton A. dos Anjos
Angelita Habr-Gama
Bruna B. Vailati
Cecilia B. Rossi
Adelina E. Coturel
Rodrigo O. Perez
Guilherme P. São Julião
João B. de Sousa
Carlos A. Buchpiguel
Publication date: 01-10-2016
Publisher: Springer Japan
Published in: Annals of Nuclear Medicine / Issue 8/2016
Print ISSN: 0914-7187
Electronic ISSN: 1864-6433
DOI: https://doi.org/10.1007/s12149-016-1089-4

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¹⁸F-FDG uptake by rectal cancer is similar in mucinous and nonmucinous histological subtypes

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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