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Annals of Nuclear Medicine

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01-04-2015 | Original Article

Role of ¹⁸F-fluoride PET/CT over dual-phase bone scintigraphy in evaluation and management of lesions causing foot and ankle pain

Authors: Ji Young Kim, Yun Young Choi, Young Hwan Kim, Si-Bog Park, Mi Ae Jeong

Published in: Annals of Nuclear Medicine | Issue 3/2015

Abstract

Objective

The purpose of this study was to assess the potential role of ¹⁸F-fluoride PET/CT over dual-phase bone scintigraphy (DBS) in evaluation and management of lesions causing foot and ankle pain.

Methods

^99mTc-HDP DBS and ¹⁸F-fluoride PET/CT were performed in consecutive patients who visited rehabilitation department due to foot or ankle pain. Focal painful lesions in fore, mid, and hindfoot or ankle, and diffuse pain in foot were evaluated on DBS and ¹⁸F-fluoride PET/CT (conclusive, inconclusive, nonvisible) and lesions on each modality were correlated. The clinical course was followed to see if the results of ¹⁸F-fluoride PET/CT affected the decision of patient management.

Results

Sixty-one painful lesions in 31 patients included 16 forefoot (26.2 %), 11 midfoot (18.0 %), 19 hindfoot (31.2 %), 6 ankle (9.8 %), and 9 diffuse footpain (14.8 %). Forty lesions (40/61, 65.6 %) were detected on DBS, including 21 conclusive diagnostic (21/40, 52.5 %), mainly including hindfoot lesions (n = 11). The inconclusive 19 lesions (19/40, 47.5 %) on DBS showed conclusive diagnostic findings on ¹⁸F-fluoride PET/CT, mainly in fore and midfoot lesions (n = 15). Twenty-one painful lesions (21/61, 34.4 %) which were nonvisible on DBS revealed conclusive diagnostic findings on ¹⁸F-fluoride PET/CT in 7 lesions (7/21, 33.3 %), including 5 hindfoot lesions. Fourteen nonvisible lesions (14/21, 66.7 %) on both modalities included all 9 diffuse painful foot lesions. Patient management was affected by findings of ¹⁸F-fluoride PET/CT in 31 lesions (31/61, 50.8 %).

Conclusions

¹⁸F-fluoride PET/CT provided more confirmative diagnostic information in painful foot and ankle over DBS, and influenced patient management in many inconclusive or nonvisible cases on DBS. Increasing role of ¹⁸F-fluoride PET/CT in benign diseases including foot and ankle pain is expected in the near future.

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Title: Role of 18F-fluoride PET/CT over dual-phase bone scintigraphy in evaluation and management of lesions causing foot and ankle pain
Authors: Ji Young Kim
Yun Young Choi
Young Hwan Kim
Si-Bog Park
Mi Ae Jeong
Publication date: 01-04-2015
Publisher: Springer Japan
Published in: Annals of Nuclear Medicine / Issue 3/2015
Print ISSN: 0914-7187
Electronic ISSN: 1864-6433
DOI: https://doi.org/10.1007/s12149-014-0942-6

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Role of ¹⁸F-fluoride PET/CT over dual-phase bone scintigraphy in evaluation and management of lesions causing foot and ankle pain

Abstract

Objective

Methods

Results

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Objective

Methods

Results

Conclusions

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