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Head and Neck Pathology
Published in: Head and Neck Pathology 1/2021

01-03-2021 | Vasculitis | Case Reports

Gingival Swelling as the Initial Manifestation of Granulomatosis with Polyangiitis

Authors: Thomas Kertesz, Medha Soowamber, Justin Bubola, David J. Psutka, Grace Bradley

Published in: Head and Neck Pathology | Issue 1/2021

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Abstract

We describe a case of granulomatosis with polyangiitis (GPA; formerly named Wegener granulomatosis) that presented initially as florid areas of gingival swelling. The patient also had upper respiratory symptoms that included sinus congestion and cough of recent onset. Clinical-pathologic correlation aided the interpretation of non-specific biopsy findings and immediate referral to an appropriate medical specialist. Treatment was rendered at an early stage of disease with a good response to date. Review of the literature indicates that gingival swelling, often with the characteristic appearance of “strawberry gingivitis” may represent the initial sign of disease in 2% of patients with GPA. Biopsy of gingival lesions often shows a non-specific histologic appearance that should be interpreted in the context of the clinical appearance and pertinent medical history. The clinical investigations that lead to definitive diagnosis and treatment are presented to facilitate the management of this uncommon but potentially fatal condition.
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Metadata
Title
Gingival Swelling as the Initial Manifestation of Granulomatosis with Polyangiitis
Authors
Thomas Kertesz
Medha Soowamber
Justin Bubola
David J. Psutka
Grace Bradley
Publication date
01-03-2021
Publisher
Springer US
Published in
Head and Neck Pathology / Issue 1/2021
Electronic ISSN: 1936-0568
DOI
https://doi.org/10.1007/s12105-020-01144-0

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