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01-07-2020 | Neuromuscular Disorders in Children | Scientific Letter

COVID-19 (SARS-CoV-2 Infection) and Children: Pediatric Neurologist’s Perspective

Authors: Prateek Kumar Panda, Indar Kumar Sharawat

Published in: Indian Journal of Pediatrics | Issue 7/2020

Excerpt

To the Editor: The currently ongoing COVID-19 pandemic has involved more than 190 countries and children are affected less frequently. Although until now no specific isolated neurotropic symptoms of COVID-19 have not been reported in children, extrapolation from adult studies reveals a minority proportion of affected cases may develop neurological symptoms due to other organ dysfunction, dyselectrolytemia, hypoxia, adverse effects of drugs and only rarely due to direct invasion of the virus into the central nervous system [1]. Ischemic stroke, seizures, hypoxic encephalopathy, acute hemorrhagic encephalopathy and Guillain-Barré syndrome have been reported in adults [1‐3]. …

Dong Y, Mo X, Hu Y, et al. Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China. Pediatrics. 2020. https://doi.org/10.1542/peds.2020-0702.

Poyiadji N, Shahin G, Noujaim D, Stone M, Patel S, Griffith B. COVID-19-associated acute hemorrhagic necrotizing encephalopathy: CT and MRI features. Radiology. 2020;201187.

Zhao H, Shen D, Zhou H, Liu J, Chen S. Guillain-Barré syndrome associated with SARS-CoV-2 infection: causality or coincidence? Lancet Neurol. 2020. Available at: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(20)30109-5. Accessed 5 Apr 2020.

Concerns About COVID-19 (Coronavirus) and Epilepsy. Epilepsy Found. Available at: https://www.epilepsy.com/article/2020/3/concerns-about-covid-19-coronavirus-and-epilepsy. Accessed Apr 5, 2020.

Yazdany J, Kim AHJ. Use of hydroxychloroquine and chloroquine during the COVID-19 pandemic: what every clinician should know. Ann Intern Med. 2020. https://doi.org/10.7326/M20-1334.

Title: COVID-19 (SARS-CoV-2 Infection) and Children: Pediatric Neurologist’s Perspective
Authors: Prateek Kumar Panda
Indar Kumar Sharawat
Publication date: 01-07-2020
Publisher: Springer India
Keywords: Neuromuscular Disorders in Children
Severe Acute Respiratory Syndrome Coronavirus
Middle Eastern Respiratory Syndrome
Acute Respiratory Distress-Syndrome
COVID-19
Epilepsy
Encephalopathy
Duchenne Muscular Dystrophy
Published in: Indian Journal of Pediatrics / Issue 7/2020
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI: https://doi.org/10.1007/s12098-020-03326-8

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