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Indian Journal of Pediatrics
Published in: Indian Journal of Pediatrics 12/2019

01-12-2019 | Spinal Muscular Atrophy | Scientific Letter

A Novel Adverse Event of Nusinersen Treatment: Thrombocytosis

Authors: Nagehan Aslan, Dincer Yildizdas, Yasemin Coban, Ozden Ozgur Horoz, Gulen Gul Mert, Neslihan Ozcan

Published in: Indian Journal of Pediatrics | Issue 12/2019

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Excerpt

To the Editor: Nusinersen (SPINRAZA-Biogen; Cambridge, MA, USA), is a new generation intrathecal treatment method for Spinal muscular atrophy (SMA) Type 1. This is an antisense oligonucleotide which produces effect by increasing SMN protein production [1]. The effects and adverse effects of the drug have not been revealed completely [2]. …
Literature
1.
2.
Goodkey K, Aslesh T, Maruyama R, et al. Nusinersen in the treatment of spinal muscular atrophy. Methods Mol Biol. 2018;1828:69–76.CrossRef
3.
4.
Chiriboga CA. Nusinersen for the treatment of spinal muscular atrophy. Expert Rev Neurother. 2017;17:955–62.CrossRef
5.
Yang CJ, Hwang JJ, Hung JY, et al. Extreme thrombocytosis under the treatment by amoxicillin/ clavulanate. Pharm World Sci. 2006;28:326–8.CrossRef
Metadata
Title
A Novel Adverse Event of Nusinersen Treatment: Thrombocytosis
Authors
Nagehan Aslan
Dincer Yildizdas
Yasemin Coban
Ozden Ozgur Horoz
Gulen Gul Mert
Neslihan Ozcan
Publication date
01-12-2019
Publisher
Springer India
Published in
Indian Journal of Pediatrics / Issue 12/2019
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-019-03069-1

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