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01-05-2018 | Editorial Commentary

Familial Hypercholesterolemia: Nip the Evil in the Bud

Authors: Bhawana Aggarwal, Neerja Gupta

Published in: Indian Journal of Pediatrics | Issue 5/2018

Excerpt

Familial Hypercholesterolemia (FH) is an autosomal dominant monogenic disorder characterised by lifetime elevation in plasma concentration of low density lipoprotein (LDL) cholesterol levels owing to impaired hepatic clearance of LDL cholesterol particles and the family history of dyslipidemia and cardiovascular disease (CVD). Various external manifestations including tendinous xanthoma, xanthelasma and corneal arcus result from deposition of low density lipoprotein-cholesterol (LDL-C) in tissues, whereas deposition in the blood vessels leads to the most dreaded complication of premature CVD. …

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Title: Familial Hypercholesterolemia: Nip the Evil in the Bud
Authors: Bhawana Aggarwal
Neerja Gupta
Publication date: 01-05-2018
Publisher: Springer India
Published in: Indian Journal of Pediatrics / Issue 5/2018
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI: https://doi.org/10.1007/s12098-018-2664-6

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