Skip to main content
Top
Published in: Indian Journal of Pediatrics 5/2018

01-05-2018 | Commentary

Economic Burden of Transfusion Dependent Thalassemia

Author: V. P. Choudhry

Published in: Indian Journal of Pediatrics | Issue 5/2018

Login to get access

Excerpt

Beta-thalassemia is the most common autosomal recessive disorder worldwide. Several surveys have been conducted including multi-centric studies under Jai Vigyan S & T mission project on community control of thalassemia syndromes and its mean prevalence is nearly 3.5% (range 1–17%) [15]. Its prevalence is high in certain communities like Sindhis, Punjabis, Khatries, Gujratis, Mahars, Lohans and in certain Muslim and Christian communities. In India, over 50 million people are carriers of thalassemia [6]. As per National Health Mission guidelines on Hemoglobinopathies in India, 10,000 to 15,000 babies with thalassemia major are born in India every year and about 1 to 1.5 lakh thalassemia patients are there in our country [7]. …
Literature
1.
go back to reference Verma IC. The challenge of genetic disorders in India. Molecular Genetics and Gene Therapy- The New Frontier. Amsterdam: Scientific Communications; 1994. p. 11–20. Verma IC. The challenge of genetic disorders in India. Molecular Genetics and Gene Therapy- The New Frontier. Amsterdam: Scientific Communications; 1994. p. 11–20.
2.
go back to reference Bashyam MD, Bashyam L, Savithri GR, Gopi Krishna M, Sangal V, Devi AR. Molecular genetic analyses of beta thalassemia in South India reveal rare mutations in the beta globin gene. J Hum Genet. 2004;49:408–13.CrossRefPubMed Bashyam MD, Bashyam L, Savithri GR, Gopi Krishna M, Sangal V, Devi AR. Molecular genetic analyses of beta thalassemia in South India reveal rare mutations in the beta globin gene. J Hum Genet. 2004;49:408–13.CrossRefPubMed
3.
go back to reference Gupta A, Hattori Y, Gupta UR, et al. Molecular genetic testing of beta-thalassemia patients of Indian origin and a novel 8bp deletion mutation at codons 36/37/38/39. Genet Test. 2003;7:163–8.CrossRefPubMed Gupta A, Hattori Y, Gupta UR, et al. Molecular genetic testing of beta-thalassemia patients of Indian origin and a novel 8bp deletion mutation at codons 36/37/38/39. Genet Test. 2003;7:163–8.CrossRefPubMed
4.
go back to reference PRB. World population data sheet. Washington DC: Population Reference Bureau; 2010. PRB. World population data sheet. Washington DC: Population Reference Bureau; 2010.
5.
go back to reference Mohanty D, Colah R, Gorakshakar A. Jai Vigyan S and T Mission Project on Community Control of Thalassemia Syndromes – Awareness, Screening, Genetic Counselling and Prevention. Published by Director-General Indian Council Medical Research; 2008. Mohanty D, Colah R, Gorakshakar A. Jai Vigyan S and T Mission Project on Community Control of Thalassemia Syndromes – Awareness, Screening, Genetic Counselling and Prevention. Published by Director-General Indian Council Medical Research; 2008.
6.
go back to reference Choudhry VP, Arora JS. Thalassemia. In: Gupta P, Menon PSN, Ramji S, Lodha R, editors. PG Textbook of Pediatric. Vol 2. Delhi: Jaypee Brothers Medical Publishers (P) Ltd; 2015. p. 1556–65. Choudhry VP, Arora JS. Thalassemia. In: Gupta P, Menon PSN, Ramji S, Lodha R, editors. PG Textbook of Pediatric. Vol 2. Delhi: Jaypee Brothers Medical Publishers (P) Ltd; 2015. p. 1556–65.
7.
go back to reference National Health Mission Guidelines on haemoglobinopathies in India. Prevention and control of haemoglobinopathies in India-thalassemia, sickle cell disease and other variant hemoglobins. Published by Ministry of Health & Family Welfare Government of India; 2016. National Health Mission Guidelines on haemoglobinopathies in India. Prevention and control of haemoglobinopathies in India-thalassemia, sickle cell disease and other variant hemoglobins. Published by Ministry of Health & Family Welfare Government of India; 2016.
8.
go back to reference Verma IC, Saxena R, Kohli S. Past, present & future scenario of thalassaemic care & control in India. Indian J Med Res. 2011;134:507–21.PubMedPubMedCentral Verma IC, Saxena R, Kohli S. Past, present & future scenario of thalassaemic care & control in India. Indian J Med Res. 2011;134:507–21.PubMedPubMedCentral
9.
go back to reference Grow K, Vashist M, Abrol P, Sharma S, Yadav R. Beta-thalassemia in India: current status and the challenges ahead. Int J Pharm Pharmaceu Sci. 2014;6:28–33. Grow K, Vashist M, Abrol P, Sharma S, Yadav R. Beta-thalassemia in India: current status and the challenges ahead. Int J Pharm Pharmaceu Sci. 2014;6:28–33.
10.
go back to reference Moirangthem A, Phadke SR. Socio-demographic profile and economic burden of treatment of transfusion dependent thalassemia. Indian J Pediatr. 2018;85:102–70.CrossRefPubMed Moirangthem A, Phadke SR. Socio-demographic profile and economic burden of treatment of transfusion dependent thalassemia. Indian J Pediatr. 2018;85:102–70.CrossRefPubMed
11.
go back to reference Shobini R. Guidelines for recovery of processing charge for blood components. NACO Guidelines. No. S. 12016/01/2012-NACO (NBTC); 2014. Shobini R. Guidelines for recovery of processing charge for blood components. NACO Guidelines. No. S. 12016/01/2012-NACO (NBTC); 2014.
13.
go back to reference Caocci G, Orofino MG, Vacca A, et al. Long-term survival of beta thalassemia major patients treated with hematopoietic stem cell transplantation compared with survival with conventional treatment. Am J Hematol. 2017;92:1303–10.CrossRefPubMed Caocci G, Orofino MG, Vacca A, et al. Long-term survival of beta thalassemia major patients treated with hematopoietic stem cell transplantation compared with survival with conventional treatment. Am J Hematol. 2017;92:1303–10.CrossRefPubMed
14.
go back to reference Cappellin MD, Cohen A, Porter J, Taher A, Viprakasit V. Guidelines for the management of transfusion dependant (TDT). Thalassemia International Federation. Publication No.20; 2014. Cappellin MD, Cohen A, Porter J, Taher A, Viprakasit V. Guidelines for the management of transfusion dependant (TDT). Thalassemia International Federation. Publication No.20; 2014.
Metadata
Title
Economic Burden of Transfusion Dependent Thalassemia
Author
V. P. Choudhry
Publication date
01-05-2018
Publisher
Springer India
Published in
Indian Journal of Pediatrics / Issue 5/2018
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-018-2642-z

Other articles of this Issue 5/2018

Indian Journal of Pediatrics 5/2018 Go to the issue