Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
Indian Journal of Pediatrics
Published in: Indian Journal of Pediatrics 12-13/2016

01-12-2016 | Scientific Letter

Salivary Cortisol Based Early ACTH Test for Identifying Adrenal Insufficiency in Low Birth Weight Infants

Authors: Ori Hochwald, Liisa Holsti, Horacio Osiovich

Published in: Indian Journal of Pediatrics | Issue 12-13/2016

Login to get access

Excerpt

To the Editor: In premature newborns, a variety of etiologies result in early hypotension [1]. Transient adrenal insufficiency (TAI) is one etiology which is difficult to diagnose in this group [2]. ACTH test is superior to random cortisol levels to diagnose TAI [3]. In a former study, an increase in serum cortisol below 12 % from baseline during ACTH study had 93 % specificity for detecting hypotension that was treated with inotropes, and thus suspected to be a clinical sign of adrenal insufficiency [4]. …
Literature
1.
Seri I. Management of hypotension and low systemic blood flow in the very low birth weight neonate during the first postnatal week. J Perinatol. 2006;26:S8–13.CrossRefPubMed
2.
Watterberg KL. Adrenocortical function and dysfunction in the fetus and neonate. Semin Neonatol. 2004;9:13–21.CrossRefPubMed
3.
Heckmann M, Wudy SA, Haack D, Pohlandt F. Reference range for serum cortisol in well preterm infants. Arch Dis Child Fetal Neonatal Ed. 1999;81:F171–4.CrossRefPubMedPubMedCentral
4.
Hochwald O, Holsti L, Osiovich H. The use of an early ACTH test to identify hypoadrenalism-related hypotension in low birth weight infants. J Perinatol. 2012;32:412–7.CrossRefPubMed
5.
Neu M, Goldstein M, Gao D, Laudenslager ML. Salivary cortisol in preterm infants: validation of a simple method for collecting saliva for cortisol determination. Early Hum Dev. 2007;83:47–54.CrossRefPubMed
Metadata
Title
Salivary Cortisol Based Early ACTH Test for Identifying Adrenal Insufficiency in Low Birth Weight Infants
Authors
Ori Hochwald
Liisa Holsti
Horacio Osiovich
Publication date
01-12-2016
Publisher
Springer India
Published in
Indian Journal of Pediatrics / Issue 12-13/2016
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-016-2177-0

Other articles of this Issue 12-13/2016

Indian Journal of Pediatrics 12-13/2016 Go to the issue

Clinical Brief

Decreased CDKN1C Expression in Congenital Alveolar Rhabdomyosarcoma Associated with Beckwith-Wiedemann Syndrome

Editorial

Editorial: Striving for Excellence in Pediatric Gastroenterology Care — A Continuous Effort

Original Article

Penile Length and Testicular Volume in Newborns

Original Article

Vitamin D Status in Infants with Two Different Wheezing Phenotypes

Scientific Letter

Alcohol Exposure in Breastfed Neonates Associated with Chinese Chicken Wine

Scientific Letter

Electrocardiographic Tremor as an Important Diagnostic Aid in Spinal Muscular Atrophy