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Published in: Indian Journal of Pediatrics 8/2016

01-08-2016 | Correspondence

Serum Vitamin D Status and Outcome among Critically Ill Children Admitted to the Pediatric Intensive Care Unit in South India: Correspondence

Author: Suresh Kumar Angurana

Published in: Indian Journal of Pediatrics | Issue 8/2016

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Excerpt

To the Editor : Recently, many studies demonstrated that the prevalence of vitamin D deficiency (VDD) among critically ill children is 25–84 % at admission to pediatric intensive care unit (PICU) [15] (Table 1). Few of them also identified that VDD is associated with greater severity of illness and longer PICU stay [1, 2, 5] which suggests that VDD has an indirect impact on hospital burden in terms of increased duration and cost of hospital stay.
Table 1
Prevalence of vitamin D deficiency (VDD) among critically ill children in different studies
S. no.
Studies Author, year
Total patients
Prevalence of VDDa (%)
1
Madden et al., 2012 [1]
511
40.1
2
McNally et al., 2012 [2]
326
69
3
Rippel et al., 2012 [3]
316
34.5
4
Rey et al., 2014
156
29.5
5
Ayulo et al., 2014
216
28
6
Hebbar et al., 2014b
61
16.4
7
Dayal et al., 2014c, d
92
25
8
Korwutthikulrangsri et al., 2015
32
78.1
9
Prasad et al., 2015d
80
83.8
10
Ponnarmeni et al., 2015d [4]
124
50.8
11
Ebenezer et al., 2015d [5]
52
40.3
aVDD was defined as 25(OH)D levels <50 nmol/L or <20 ng/ml in most of the studies
bVDD was defined as 25(OH)D levels <25 nmol/L. In this study, 60.7 % of children in PICU had 25(OH)D levels <50 nmol/L
cThis study included children hospitalized to a general Pediatric unit of a tertiary care center in North India
dIndian studies
Literature
2.
go back to reference McNally JD, Menon K, Chakraborty P, et al. The association of vitamin D status with pediatric critical illness. Pediatrics. 2012;130:429–36.CrossRefPubMed McNally JD, Menon K, Chakraborty P, et al. The association of vitamin D status with pediatric critical illness. Pediatrics. 2012;130:429–36.CrossRefPubMed
3.
go back to reference Rippel C, South M, Butt WW, Shekerdemian LS. Vitamin D status in critically ill children. Intensive Care Med. 2012;38:2055–62.CrossRefPubMed Rippel C, South M, Butt WW, Shekerdemian LS. Vitamin D status in critically ill children. Intensive Care Med. 2012;38:2055–62.CrossRefPubMed
4.
go back to reference Ponnarmeni S, Kumar Angurana S, Singhi S, et al. Vitamin D deficiency in critically ill children with sepsis. Paediatr Int Child Health. 2015:2046905515Y0000000042. Ponnarmeni S, Kumar Angurana S, Singhi S, et al. Vitamin D deficiency in critically ill children with sepsis. Paediatr Int Child Health. 2015:2046905515Y0000000042.
5.
go back to reference Ebenezer K, Job V, Antonisamy B, Dawodu A, Manivachagan MN, Steinhoff M. Serum vitamin D status and outcome among critically ill children admitted to the pediatric intensive care unit in South India. Indian J Pediatr. 2015. doi:10.1007/s12098-015-1833-0.PubMed Ebenezer K, Job V, Antonisamy B, Dawodu A, Manivachagan MN, Steinhoff M. Serum vitamin D status and outcome among critically ill children admitted to the pediatric intensive care unit in South India. Indian J Pediatr. 2015. doi:10.​1007/​s12098-015-1833-0.PubMed
Metadata
Title
Serum Vitamin D Status and Outcome among Critically Ill Children Admitted to the Pediatric Intensive Care Unit in South India: Correspondence
Author
Suresh Kumar Angurana
Publication date
01-08-2016
Publisher
Springer India
Published in
Indian Journal of Pediatrics / Issue 8/2016
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-015-1992-z

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