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Indian Journal of Pediatrics
Published in: Indian Journal of Pediatrics 11/2015

01-11-2015 | Original Article

Vitamin D Deficiency and Critical Illness

Authors: Shailender Prasad, Dinesh Raj, Sumbul Warsi, Sona Chowdhary

Published in: Indian Journal of Pediatrics | Issue 11/2015

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Abstract

Objective

To determine the prevalence of vitamin D deficiency in critically ill children and assess its association with severity of illness and other outcomes associated with critical illness.

Methods

Eighty children aged 2mo to 12y, admitted with medical conditions to the pediatric intensive care unit of a tertiary care hospital were enrolled in this prospective observational study. Vitamin D levels were obtained during the first hour of stay. Severity score was assessed using the Pediatric Risk of Mortality III (PRISM III) within first 12 h of admission.

Results

Vitamin D deficiency {25-hydroxy vitamin D [25(OH)D] levels < 20 ng/ml} was observed in 67 (83.8 %) children. Vitamin D deficient children had significantly higher PRISM III score compared to vitamin D sufficient children [10 (IQR:5–15) vs. 6 (IQR:3–7); p 0.0099]. 25(OH)D levels had a significant negative correlation with PRISM III score (ρ -0.3747; p 0.0006).

Conclusions

Vitamin D appears to be of utmost importance in critically ill children.
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Metadata
Title
Vitamin D Deficiency and Critical Illness
Authors
Shailender Prasad
Dinesh Raj
Sumbul Warsi
Sona Chowdhary
Publication date
01-11-2015
Publisher
Springer India
Published in
Indian Journal of Pediatrics / Issue 11/2015
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-015-1778-3

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