Published in:
01-06-2010 | Letter to the Editor
Intravenous N-acetylcysteine in dengue-associated acute liver failure
Authors:
Ravindu S. Kumarasena, S. Mananjala Senanayake, Krishan Sivaraman, Arjuna P. de Silva, Anuradha S. Dassanayake, Ranjan Premaratna, Bandula Wijesiriwardena, H. Janaka de Silva
Published in:
Hepatology International
|
Issue 2/2010
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Excerpt
We read with interest the article by Mumtaz et al. [
1] on the role of oral
N-acetylcysteine (NAC) in adults with non-acetaminophen-induced acute liver failure. We agree that their findings are of particular relevance to many developing countries, where liver transplantation is neither available nor affordable. There has been another recent study in which intravenous NAC has been shown to improve transplant-free survival in early-stage non-acetaminophen-induced acute liver failure in adults [
2]. We report our initial experience in treating acute liver failure caused by dengue infection with NAC. Use of NAC in this situation has not been previously described. …
