Skip to main content
Top
Published in: Indian Journal of Otolaryngology and Head & Neck Surgery 1/2016

01-03-2016 | Clinical Report

Huge Respiratory Epithelial Adenomatoid Hamartoma Originating from the Inferior Nasal Turbinate: A Case Report

Authors: Aleksandar Perić, Dušan Bijelić, Biserka Vukomanović-Đurđević, Aneta V. Perić

Published in: Indian Journal of Otolaryngology and Head & Neck Surgery | Issue 1/2016

Login to get access

Abstract

Respiratory epithelial adenomatoid hamartoma (REAH) is a recently described entity consisted of benign glandular proliferations lined by pseudostratified respiratory epithelium. We report a case of a 22-year-old male patient with 7-year history of nasal obstruction and headache resulting from a huge left-sided nasal lesion. Computed tomography, magnetic resonance and biopsy were performed to make a provisional diagnosis of REAH originating from the left-sided inferior turbinate. The definitive diagnosis of REAH was made by histopathological examination of the removed mass. We also discuss the origin and differential diagnosis of these rare lesions.
Literature
1.
go back to reference Wenig BM, Heffner DK (1995) Respiratory epithelial adenomatoid hamartomas of the sinonasal tract and nasopharynx: a clinicopathological study of 31 cases. Ann Otol Rhinol Laryngol 104:639–645CrossRefPubMed Wenig BM, Heffner DK (1995) Respiratory epithelial adenomatoid hamartomas of the sinonasal tract and nasopharynx: a clinicopathological study of 31 cases. Ann Otol Rhinol Laryngol 104:639–645CrossRefPubMed
2.
go back to reference Lee JT, Garg R, Brunworth J, Keschner DB, Thompson LDR (2013) Sinonasal respiratory epithelial adenomatoid hamartomas: series of 51 cases and literature review. Am J Rhinol Allergy 27:322–328CrossRefPubMed Lee JT, Garg R, Brunworth J, Keschner DB, Thompson LDR (2013) Sinonasal respiratory epithelial adenomatoid hamartomas: series of 51 cases and literature review. Am J Rhinol Allergy 27:322–328CrossRefPubMed
3.
go back to reference Ozolek JA, Hunt JL (2006) Tumor suppressor gene alterations in respiratory epithelial adenomatoid hamartoma (REAH): comparison to sinonasal adenocarcinoma and inflamed sinonasal mucosa. Am J Surg Pathol 30:1576–1580CrossRefPubMed Ozolek JA, Hunt JL (2006) Tumor suppressor gene alterations in respiratory epithelial adenomatoid hamartoma (REAH): comparison to sinonasal adenocarcinoma and inflamed sinonasal mucosa. Am J Surg Pathol 30:1576–1580CrossRefPubMed
4.
go back to reference Lorentz C, Marie B, Vignaud JM, Jankowski R (2012) Respiratory epithelial adenomatoid hamartomas of the olfactory clefts. Eur Arch Otorhinolaryngol 269:847–852CrossRefPubMed Lorentz C, Marie B, Vignaud JM, Jankowski R (2012) Respiratory epithelial adenomatoid hamartomas of the olfactory clefts. Eur Arch Otorhinolaryngol 269:847–852CrossRefPubMed
5.
go back to reference Lima NB, Jankowski R, Georgel T, Grignon B, Guillemin F, Vignaud JM (2006) Respiratory adenomatoid hamartoma must be suspected on CT-scan enlargement of the olfactory clefts. Rhinology 44:264–269PubMed Lima NB, Jankowski R, Georgel T, Grignon B, Guillemin F, Vignaud JM (2006) Respiratory adenomatoid hamartoma must be suspected on CT-scan enlargement of the olfactory clefts. Rhinology 44:264–269PubMed
6.
go back to reference Endo R, Matsuda H, Takahashi M, Hara M, Inaba H, Tsukuda M (2002) Respiratory epithelial adenomatoid hamartoma in the nasal cavity. Acta Otolaryngol 122:398–400CrossRefPubMed Endo R, Matsuda H, Takahashi M, Hara M, Inaba H, Tsukuda M (2002) Respiratory epithelial adenomatoid hamartoma in the nasal cavity. Acta Otolaryngol 122:398–400CrossRefPubMed
7.
go back to reference Nguyen DT, Nguyen-Thi PL, Gauchotte G, Arous F, Vignaud JM, Jankowski R (2014) Predictors of respiratory epithelial adenomatoid hamartomas of the olfactory clefts in patients with nasal polyposis. Laryngoscope 124:2461–2465CrossRefPubMed Nguyen DT, Nguyen-Thi PL, Gauchotte G, Arous F, Vignaud JM, Jankowski R (2014) Predictors of respiratory epithelial adenomatoid hamartomas of the olfactory clefts in patients with nasal polyposis. Laryngoscope 124:2461–2465CrossRefPubMed
8.
go back to reference Fedda F, Boulos F, Sabri A (2013) Chondro-osseous respiratory epithelial adenomatoid hamartoma of the nasal cavity. Int Arch Otorhinolaryngol 17:218–221CrossRefPubMedPubMedCentral Fedda F, Boulos F, Sabri A (2013) Chondro-osseous respiratory epithelial adenomatoid hamartoma of the nasal cavity. Int Arch Otorhinolaryngol 17:218–221CrossRefPubMedPubMedCentral
9.
go back to reference Cao ZW, Gu ZW, Yang J, Jin MZ (2010) Respiratory epithelial adenomatoid hamartoma of bilateral olfactory clefts associated with nasal polyposis: three case report and literature review. Auris Nasus Larynx 37:352–356CrossRefPubMed Cao ZW, Gu ZW, Yang J, Jin MZ (2010) Respiratory epithelial adenomatoid hamartoma of bilateral olfactory clefts associated with nasal polyposis: three case report and literature review. Auris Nasus Larynx 37:352–356CrossRefPubMed
10.
go back to reference Kaneko C, Inokuchi A, Kimitsuki T, Kumamoto Y, Shinokuma A, Natori Y et al (1999) Huge hamartoma with inverted papilloma in the nasal cavity. Eur Arch Otorhinolaryngol 256:S33–S37CrossRefPubMed Kaneko C, Inokuchi A, Kimitsuki T, Kumamoto Y, Shinokuma A, Natori Y et al (1999) Huge hamartoma with inverted papilloma in the nasal cavity. Eur Arch Otorhinolaryngol 256:S33–S37CrossRefPubMed
Metadata
Title
Huge Respiratory Epithelial Adenomatoid Hamartoma Originating from the Inferior Nasal Turbinate: A Case Report
Authors
Aleksandar Perić
Dušan Bijelić
Biserka Vukomanović-Đurđević
Aneta V. Perić
Publication date
01-03-2016
Publisher
Springer India
Published in
Indian Journal of Otolaryngology and Head & Neck Surgery / Issue 1/2016
Print ISSN: 2231-3796
Electronic ISSN: 0973-7707
DOI
https://doi.org/10.1007/s12070-015-0849-0

Other articles of this Issue 1/2016

Indian Journal of Otolaryngology and Head & Neck Surgery 1/2016 Go to the issue