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Indian Journal of Thoracic and Cardiovascular Surgery
Published in: Indian Journal of Thoracic and Cardiovascular Surgery 4/2017

01-12-2017 | Case report

Significant pulmonary disease burden in treatment resistant disseminated cryptococcal infection: A case report

Authors: Shanthi Viswanathan Shanthakumar, Sharon Mei Ling Tai, Abdul Rais Sanusi, Sivakumar Sivalingam, Saad Bader Zakai

Published in: Indian Journal of Thoracic and Cardiovascular Surgery | Issue 4/2017

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Abstract

Cryptococcus neoformans causes severe disseminated infection in immunocompromised individuals. We report a case of an immunocompetent adult male who presented with treatment-resistant central nervous system manifestations and significant pulmonary disease burden. Hematology and lumbar puncture were positive, aided by computerized tomography-guided histological confirmation. Despite medical therapy, there was inadequate resolution, and surgical resection was performed. On follow-up, investigations showed complete resolution, and the patient has remained disease-free at 5 years. This highlights the importance of looking for other sites in resistant cryptococcal meningitis and the value of cardiothoracic intervention for slowly resolving pulmonary cryptococcomas.
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Metadata
Title
Significant pulmonary disease burden in treatment resistant disseminated cryptococcal infection: A case report
Authors
Shanthi Viswanathan Shanthakumar
Sharon Mei Ling Tai
Abdul Rais Sanusi
Sivakumar Sivalingam
Saad Bader Zakai
Publication date
01-12-2017
Publisher
Springer Singapore
Published in
Indian Journal of Thoracic and Cardiovascular Surgery / Issue 4/2017
Print ISSN: 0970-9134
Electronic ISSN: 0973-7723
DOI
https://doi.org/10.1007/s12055-017-0545-7

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