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01-01-2017 | Review Article

CTC clusters in cancer progression and metastasis

Authors: Anna Fabisiewicz, Ewa Grzybowska

Published in: Medical Oncology | Issue 1/2017

Abstract

Circulating tumor cells (CTC) in the blood of cancer patients are regarded as potential metastatic seeds, and their detailed characterization holds great promises for more exact prognosis, better diagnosis and therapy of the metastatic cancer. Circulating tumor cell clusters represent different class of CTCs, with specific properties, including high metastatic potential. In this review, we present current opinions on differences between single CTCs and CTC clusters, their mode of dissemination, methods of detection and clinical importance in various types of cancer.

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Title: CTC clusters in cancer progression and metastasis
Authors: Anna Fabisiewicz
Ewa Grzybowska
Publication date: 01-01-2017
Publisher: Springer US
Published in: Medical Oncology / Issue 1/2017
Print ISSN: 1357-0560
Electronic ISSN: 1559-131X
DOI: https://doi.org/10.1007/s12032-016-0875-0

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