Skip to main content
Top

27-11-2023 | Gastrectomy | Case Report

A Successful Central Gastrectomy and Gastro-Gastric Anastomosis for a Large Gastric GIST

Authors: Mohamed Zidan, Eslam Hassan, Mostafa Refaie

Published in: Journal of Gastrointestinal Cancer

Login to get access

Abstract

Purpose

Partial gastrectomy is always the preferred technique for GIST resection. Central gastrectomy is a practical technique that can be employed in many situations during the resection of both subepithelial stromal tumors and gastric tumors.

Case presentation

A 53-year-old Egyptian female patient with a 15 × 19 cm large fungating gastric GIST managed by central gastrectomy. Central gastrectomy and gastro-gastric anastomosis were performed with negative resection margins, and the patient received post-operative imatinib, achieving disease control throughout an 8-month post-operative follow-up.

Conclusion

Central gastrectomy is an effective method of partial gastrectomy that can be considered in GIST resection; however, more studies are needed to evaluate the efficiency of central gastrectomy in terms of long-term follow-up and terms of R0 respectability in gastric cancer.
Literature
1.
go back to reference Miettinen M, Lasota J. Gastrointestinal stromal tumors: review on morphology, molecular pathology, prognosis, and differential diagnosis. Arch Pathol Lab Med. 2006;130(10):1466–78.CrossRefPubMed Miettinen M, Lasota J. Gastrointestinal stromal tumors: review on morphology, molecular pathology, prognosis, and differential diagnosis. Arch Pathol Lab Med. 2006;130(10):1466–78.CrossRefPubMed
2.
go back to reference Joensuu H. Risk stratification of patients diagnosed with gastrointestinal stromal tumor. Hum Pathol. 2008;39(10):1411–9.CrossRefPubMed Joensuu H. Risk stratification of patients diagnosed with gastrointestinal stromal tumor. Hum Pathol. 2008;39(10):1411–9.CrossRefPubMed
3.
go back to reference Nishida T, Blay JY, Hirota S, Kitagawa Y, Kang YK. The standard diagnosis, treatment, and follow-up of gastrointestinal stromal tumors based on guidelines. Gastric Cancer. 2016;19(1):3–14.CrossRefPubMed Nishida T, Blay JY, Hirota S, Kitagawa Y, Kang YK. The standard diagnosis, treatment, and follow-up of gastrointestinal stromal tumors based on guidelines. Gastric Cancer. 2016;19(1):3–14.CrossRefPubMed
4.
5.
go back to reference Fong Y, Coit DG, Woodruff JM, Brennan MF. Lymph node metastasis from soft tissue sarcoma in adults. Analysis of data from a prospective database of 1772 sarcoma patients. Ann Surg. 1993;217(1):72–7. Fong Y, Coit DG, Woodruff JM, Brennan MF. Lymph node metastasis from soft tissue sarcoma in adults. Analysis of data from a prospective database of 1772 sarcoma patients. Ann Surg. 1993;217(1):72–7.
6.
go back to reference Demetri GD, von Mehren M, Antonescu CR, DeMatteo RP, Ganjoo KN, Maki RG, Pisters PW, Raut CP, Riedel RF, Schuetze S, et al. NCCN Task Force report: update on the management of patients with gastrointestinal stromal tumors. J Natl Compr Canc Netw 2010;8(2):S1–41. Demetri GD, von Mehren M, Antonescu CR, DeMatteo RP, Ganjoo KN, Maki RG, Pisters PW, Raut CP, Riedel RF, Schuetze S, et al. NCCN Task Force report: update on the management of patients with gastrointestinal stromal tumors. J Natl Compr Canc Netw 2010;8(2):S1–41.
7.
go back to reference Koga T, Hirayama Y, Yoshiya S, Taketani K, Nakanoko T, Yoshida R, Minagawa R, Kai M, Kajiyama K, Akahoshi K, et al. Necessity for resection of gastric gastrointestinal stromal tumors </= 20 mm. Anticancer Res. 2015;35(4):2341–4.PubMed Koga T, Hirayama Y, Yoshiya S, Taketani K, Nakanoko T, Yoshida R, Minagawa R, Kai M, Kajiyama K, Akahoshi K, et al. Necessity for resection of gastric gastrointestinal stromal tumors </= 20 mm. Anticancer Res. 2015;35(4):2341–4.PubMed
8.
go back to reference Otani Y, Furukawa T, Yoshida M, Saikawa Y, Wada N, Ueda M, Kubota T, Mukai M, Kameyama K, Sugino Y, et al. Operative indications for relatively small (2–5 cm) gastrointestinal stromal tumor of the stomach based on analysis of 60 operated cases. Surgery. 2006;139(4):484–92.CrossRefPubMed Otani Y, Furukawa T, Yoshida M, Saikawa Y, Wada N, Ueda M, Kubota T, Mukai M, Kameyama K, Sugino Y, et al. Operative indications for relatively small (2–5 cm) gastrointestinal stromal tumor of the stomach based on analysis of 60 operated cases. Surgery. 2006;139(4):484–92.CrossRefPubMed
9.
go back to reference van der Zwan SM, DeMatteo RP. Gastrointestinal stromal tumor: 5 years later. Cancer. 2005;104(9):1781–8.CrossRefPubMed van der Zwan SM, DeMatteo RP. Gastrointestinal stromal tumor: 5 years later. Cancer. 2005;104(9):1781–8.CrossRefPubMed
10.
go back to reference Carucci LR. 35 - postoperative stomach and duodenum. In: Gore RM, Levine MS, editors. Textbook of Gastrointestinal Radiology, vol. 2. 4th ed. Philadelphia: W.B. Saunders; 2015. p. 630–56. Carucci LR. 35 - postoperative stomach and duodenum. In: Gore RM, Levine MS, editors. Textbook of Gastrointestinal Radiology, vol. 2. 4th ed. Philadelphia: W.B. Saunders; 2015. p. 630–56.
11.
go back to reference Ren YX, He M, Ye PC, Wei SJ. Total laparoscopic segmental gastrectomy for gastrointestinal stromal tumors: a case report. World J Clin Cases. 2020;8(15):3365–71.CrossRefPubMedPubMedCentral Ren YX, He M, Ye PC, Wei SJ. Total laparoscopic segmental gastrectomy for gastrointestinal stromal tumors: a case report. World J Clin Cases. 2020;8(15):3365–71.CrossRefPubMedPubMedCentral
12.
go back to reference Cordera F, Salazar-Vitale A, Mejia-Sanchez E, Arrangoiz R, Caba-Molina D, Munoz-Juarez M, Luque-de-Leon E, Moreno-Paquentin E. Laparoscopic resection of gastric schwannoma: a case report. Int J Surg Case Rep. 2019;65:271–4.CrossRefPubMedPubMedCentral Cordera F, Salazar-Vitale A, Mejia-Sanchez E, Arrangoiz R, Caba-Molina D, Munoz-Juarez M, Luque-de-Leon E, Moreno-Paquentin E. Laparoscopic resection of gastric schwannoma: a case report. Int J Surg Case Rep. 2019;65:271–4.CrossRefPubMedPubMedCentral
13.
go back to reference Iseki J, Takagi M, Touyama K, Sano K, Nakagami K, Ori T, Ooba N, Kin H, Kojima H, Kojima K. Editorial comment: feasibility of central gastrectomy for gastric cancer. Surgery. 2003;133(1):68–73.CrossRefPubMed Iseki J, Takagi M, Touyama K, Sano K, Nakagami K, Ori T, Ooba N, Kin H, Kojima H, Kojima K. Editorial comment: feasibility of central gastrectomy for gastric cancer. Surgery. 2003;133(1):68–73.CrossRefPubMed
Metadata
Title
A Successful Central Gastrectomy and Gastro-Gastric Anastomosis for a Large Gastric GIST
Authors
Mohamed Zidan
Eslam Hassan
Mostafa Refaie
Publication date
27-11-2023
Publisher
Springer US
Published in
Journal of Gastrointestinal Cancer
Print ISSN: 1941-6628
Electronic ISSN: 1941-6636
DOI
https://doi.org/10.1007/s12029-023-00992-7
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.