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01-09-2018 | Case Report

Brain Metastasis as Initial Presentation of Rectal Adenocarcinoma: an Unusual Case in a Very Young Patient

Authors: Jyotsana Sinha, Rong Zhang, Vinit V. Patil, Miguel A Guzman, Nishant Poddar

Published in: Journal of Gastrointestinal Cancer | Issue 3/2018

Excerpt

Colorectal cancer [CRC] is the third most commonly diagnosed and cause of cancer related deaths in both genders in the USA [1].The incidence varies by age and is most common among adults >50 years [2]. Brain metastasis is rare with an incidence of 1–4% [3].Most brain metastases develop during the course of disease while the presence at initial presentation is rare. RAS mutation is associated with metastasis in CRC [4]. We present a 36-year-old male with brain metastasis as the initial presentation of a RAS unmutated rectal adenocarcinoma with microsatellite instability [MSI] and multiple synchronous metastases. …

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Title: Brain Metastasis as Initial Presentation of Rectal Adenocarcinoma: an Unusual Case in a Very Young Patient
Authors: Jyotsana Sinha
Rong Zhang
Vinit V. Patil
Miguel A Guzman
Nishant Poddar
Publication date: 01-09-2018
Publisher: Springer US
Published in: Journal of Gastrointestinal Cancer / Issue 3/2018
Print ISSN: 1941-6628
Electronic ISSN: 1941-6636
DOI: https://doi.org/10.1007/s12029-016-9911-8

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