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01-09-2018 | Case Report

What Do We Need to Know About Colonic Polypoid Ganglioneuroma? A Case Report and A Comprehensive Review

Authors: Mohamed Abdelfatah, George Sangah, Glenn Harvin

Published in: Journal of Gastrointestinal Cancer | Issue 3/2018

Excerpt

Intestinal ganglioneuromas (GNs) are rare well-differentiated, slowly growing neuroectodermal neoplasms mainly formed of nerve fibers, ganglion cells, and supporting cells [1]. There are three types of GNs: polypoid GNs, ganglioneuromatous polyposis, and diffuse ganglioneuromatosis. Polypoid GNs are the most common type and are typically found incidentally on colonoscopies as a solitary polyp involving the mucosa and submucosa that could resemble an adenoma, a hyperplastic, or a juvenile polyp. Ganglioneuromatous polyposis is characterized by more than 20 sessile or pedunculated mucosal or submucosal lesions that endoscopically resemble familial adenomatous polyposis. Diffuse ganglioneuromatosis is a large poorly-demarcated nodular and disseminated proliferation of ganglioneuromatous tissue [1]. Typically, ganglioneuromatosis are large (up to 17 cm), poorly demarcated, and often infiltrate the adjacent bowel wall and distort the surrounding tissue architecture. …

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Title: What Do We Need to Know About Colonic Polypoid Ganglioneuroma? A Case Report and A Comprehensive Review
Authors: Mohamed Abdelfatah
George Sangah
Glenn Harvin
Publication date: 01-09-2018
Publisher: Springer US
Published in: Journal of Gastrointestinal Cancer / Issue 3/2018
Print ISSN: 1941-6628
Electronic ISSN: 1941-6636
DOI: https://doi.org/10.1007/s12029-016-9892-7

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