Published in:
01-12-2016 | Case Report
Late Recurrence of Low-Risk Stage II Colorectal Cancer Shortly After Etanercept
Authors:
Tony Ibrahim, Khalil Saleh, Viviane Track-smayra, Nelly Ziade, Dalia Sarraf, Charbel Yazbeck, Nadine Khalife, Fadi Nasr
Published in:
Journal of Gastrointestinal Cancer
|
Issue 4/2016
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Excerpt
Tumor necrosis factor alpha (TNF alpha), as its name would indicate, is an immunomodulatory cytokine shown to have anti-tumor activity [
1]. The use of TNF alpha inhibitors in rheumatologic diseases has grown substantially, but debate has emerged regarding the administration of these agents to patients known to have a history of solid malignancies in remission [
2,
3]. We present here a case of systemic recurrence of low-risk colorectal cancer after the use of etanercept, a TNF alpha-sequestering agent. …