Published in:
01-03-2016 | Case Report
Neuroendocrine Carcinoma of the Gallbladder Masquerading as a Klatskin Tumor in a 74-Year-Old Male
Authors:
Fabian Kütting, Matthias Schmidt, Dirk Waldschmidt, Harald Curth, Christoph Schramm, Hans-Michael Steffen
Published in:
Journal of Gastrointestinal Cancer
|
Issue 1/2016
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Excerpt
Neuroendocrine carcinomas represent a heterogeneous tumor entity, which can occur in almost all organ systems of the human body. The worldwide incidence, approximately 0.5–5/100.000, is low, with almost 70 % occurring in the digestive system, another 20 % being diagnosed in the bronchopulmonary tract. Data from autopsy studies suggest that neuroendocrine tumors are an under-recognized malignancy [
3]. Only 0.2 % of all neuroendocrine tumors (NETs) are located in the gallbladder. The most important prognostic factor is the level of proliferation, which determines the tumor grading. Overall, poorly differentiated NETs are aggressive tumors bearing a poor prognosis. …
