Published in:
01-06-2015 | Case Report
Cases of Spontaneous Tumor Regression in Hepatobiliary Cancers: Implications for Immunotherapy?
Authors:
Anna L. Parks, Ryan M. McWhirter, Kimberley Evason, Robin K. Kelley
Published in:
Journal of Gastrointestinal Cancer
|
Issue 2/2015
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Excerpt
Hepatobiliary cancers, including hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (CCA), together comprise the fifth most common cancer and third leading cause of cancer death globally [
1]. The majority of patients present with advanced, unresectable disease, with median survival less than a year [
2‐
4]. Immune dysregulation may contribute to hepatobiliary carcinogenesis, though mechanisms are not well understood [
5‐
7]. …