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Published in:

01-10-2019 | Miscarriage | Review

Thyroid hormone therapy of hypothyroidism in pregnancy

Authors: Zhongyan Shan, Weiping Teng

Published in: Endocrine | Issue 1/2019

Abstract

Hypothyroidism is the most frequent pregnancy-related thyroid dysfunction, including overt and subclinical hypothyroidism. Studies show that even mild hypothyroidism may eventuate in adverse gestational outcomes and intellectual impairment of offspring. Women with overt hypothyroidism (OH) must be treated by levothyroxine (LT4) pre- and during pregnancy, however, it is controversial that when and how to initiate LT4 therapy and further optimize dosing so that pregnant women and their offspring may truly benefit. In the review we will analyze the changes in thyroid hormone requirements in pregnant women, the timing of LT4 treatment and adjustment of LT4 dose according to etiology in patients with hypothyroidism during pregnancy, and adjustment of LT4 after delivery.

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Title: Thyroid hormone therapy of hypothyroidism in pregnancy
Authors: Zhongyan Shan
Weiping Teng
Publication date: 01-10-2019
Publisher: Springer US
Keywords: Miscarriage
Hypothyroidism
Levothyroxine
Published in: Endocrine / Issue 1/2019
Print ISSN: 1355-008X
Electronic ISSN: 1559-0100
DOI: https://doi.org/10.1007/s12020-019-02044-2

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Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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Other articles of this Issue 1/2019

Thyroid hormone therapy in congenital hypothyroidism and pediatric hypothyroidism

Diagnosis and treatment of hypothyroidism in the elderly

Novel uses of thyroid hormones in cardiovascular conditions

T4 + T3 combination therapy: any progress?

The isolation of thyroxine (T4), the discovery of 3,5,3’-triiodothyronine (T3), and the identification of the deiodinases that generate T3 from T4: An historical review

Thyroid hormone therapy for subclinical hypothyroidism

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