Published in:
01-01-2016 | Editorial
Periostin on the road to nonalcoholic fatty liver disease
Authors:
Stergios A. Polyzos, Athanasios D. Anastasilakis
Published in:
Endocrine
|
Issue 1/2016
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Excerpt
Nonalcoholic fatty liver disease (NAFLD) is a global public health issue, affecting approximately one-third of the general population. NAFLD ranges from nonalcoholic simple steatosis (SS) to nonalcoholic steatohepatitis (NASH), characterized by inflammation and/or fibrosis, NASH-related cirrhosis and hepatocellular carcinoma [
1]. Liver biopsy remains the gold standard in the diagnosis of NAFLD, although identification of noninvasive biomarkers is a field of intense research [
2]. Even more, despite its high prevalence, the treatment of NAFLD currently remains an unmet medical need [
3]. …