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Endocrine
Published in: Endocrine 3/2016

01-09-2016 | Review

False positive diagnosis on 131iodine whole-body scintigraphy of differentiated thyroid cancers

Authors: Vincenzo Triggiani, Vito Angelo Giagulli, Michele Iovino, Giovanni De Pergola, Brunella Licchelli, Antonio Varraso, Franca Dicembrino, Guido Valle, Edoardo Guastamacchia

Published in: Endocrine | Issue 3/2016

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Abstract

131Iodine is used both to ablate any residual thyroid tissue or metastatic disease and to obtain whole-body diagnostic images after total thyroidectomy for differentiated thyroid cancer (DTC). Even though whole-body scan is highly accurate in showing thyroid residues as well as metastases of DTC, false positive results can be found, possibly leading to diagnostic errors and unnecessary treatments. This paper reviews the physiological and pathological processes involved as well as the strategy to recognize and rule out false positive radioiodine images.
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Metadata
Title
False positive diagnosis on 131iodine whole-body scintigraphy of differentiated thyroid cancers
Authors
Vincenzo Triggiani
Vito Angelo Giagulli
Michele Iovino
Giovanni De Pergola
Brunella Licchelli
Antonio Varraso
Franca Dicembrino
Guido Valle
Edoardo Guastamacchia
Publication date
01-09-2016
Publisher
Springer US
Published in
Endocrine / Issue 3/2016
Print ISSN: 1355-008X
Electronic ISSN: 1559-0100
DOI
https://doi.org/10.1007/s12020-015-0750-3

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