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01-04-2016 | Research Letter

Elevated 1-hour plasma glucose levels are associated with dysglycemia, impaired beta-cell function, and insulin sensitivity: a pilot study from a real world health care setting

Authors: Ram Jagannathan, Mary Ann Sevick, Huilin Li, Dorothy Fink, Rachel Dankner, Angela Chetrit, Jesse Roth, Michael Bergman

Published in: Endocrine | Issue 1/2016

Excerpt

Individuals with prediabetes, namely impaired glucose tolerance (IGT) and/or impaired fasting glucose (IFG), are at increased risk of developing type 2 diabetes mellitus (T2DM) and cardiovascular disease. However, only 30–40 % of those with IFG/IGT eventually develop T2DM [1‐3]. In fact, about 40 % of individuals who develop T2DM after 10 years have Normal Glucose Tolerance (NGT) at baseline [3], indicating that the conventional fasting and 2-h oral glucose tolerance test (OGTT) do not recognize most high-risk individuals. …

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Title: Elevated 1-hour plasma glucose levels are associated with dysglycemia, impaired beta-cell function, and insulin sensitivity: a pilot study from a real world health care setting
Authors: Ram Jagannathan
Mary Ann Sevick
Huilin Li
Dorothy Fink
Rachel Dankner
Angela Chetrit
Jesse Roth
Michael Bergman
Publication date: 01-04-2016
Publisher: Springer US
Published in: Endocrine / Issue 1/2016
Print ISSN: 1355-008X
Electronic ISSN: 1559-0100
DOI: https://doi.org/10.1007/s12020-015-0746-z

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