Published in:
01-12-2012 | Letter to the Editor
Metformin and human uterine contractility
Authors:
Mark P. Hehir, John J. Morrison
Published in:
Endocrine
|
Issue 3/2012
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Excerpt
Metformin is primarily used clinically in the treatment of type 2 diabetes mellitus but in recent years has been suggested as a treatment for gestational diabetes mellitus (GDM) [
1]. It has also been increasingly prescribed in the treatment of polycystic ovarian syndrome, and for recurrent early pregnancy loss in women with PCOS. Although Metformin has been used with increasing frequency in GDM, due to a lack of complete clinical data, its use has not gained universal acceptance. Tight glycemic control during pregnancy has, however been shown to bring both fetal and maternal benefits in cases of type 1 and type 2 diabetes [
2]. …