Published in:
01-06-2014 | Introduction
Past, Present and Future of Muscle–Bone Interactions
Published in: Clinical & Translational Metabolism | Issue 2/2014
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…As a consequence of primary shape variations and continuous loading, or even due to loading alone, bone changes its inner architecture according to mathematical rules and, as a secondary effect and governed by the same mathematical rules, also changes its shape.Julius Wolff (1836–1902), in The Law of Bone Transformation (Das Gesetz der Transformation der Knochen), Berlin, A. Hirschwald, 1892.