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Clinical Orthopaedics and Related Research®

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01-09-2017 | CORR Insights

CORR Insights^®: Venous Thromboembolism Prophylaxis After TKA: Aspirin, Warfarin, Enoxaparin, or Factor Xa Inhibitors?

Author: Daniel R. Whiting, MD

Published in: Clinical Orthopaedics and Related Research® | Issue 9/2017

Excerpt

In the early era of TKA 40% to 80% of patients developed postoperative venous thromboembolism (VTE) [5, 13]. Although clinicians identified a large portion of these patients during routine postoperative screening studies and found those clots were resolved on followup imaging, great efforts were made to decrease VTE and its associated morbidity and mortality. Patients now mobilize much earlier thanks in large part to improvements in controlling pain and nausea with multimodal analgesia. Early mobilization can generally mitigate the venous stasis portion of Virchow’s triad of stasis, hypercoaguability, and intimal injury. Pharmacologic prophylaxis seeks to address the hypercoagulable state of the patient who may not be very mobile in the days immediately after surgery. …

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Title: CORR Insights®: Venous Thromboembolism Prophylaxis After TKA: Aspirin, Warfarin, Enoxaparin, or Factor Xa Inhibitors?
Author: Daniel R. Whiting, MD
Publication date: 01-09-2017
Publisher: Springer US
Published in: Clinical Orthopaedics and Related Research® / Issue 9/2017
Print ISSN: 0009-921X
Electronic ISSN: 1528-1132
DOI: https://doi.org/10.1007/s11999-017-5435-1

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CORR Insights^®: Venous Thromboembolism Prophylaxis After TKA: Aspirin, Warfarin, Enoxaparin, or Factor Xa Inhibitors?

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