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Clinical Orthopaedics and Related Research®

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01-01-2013 | Symposium: Papers Presented at the Annual Meetings of the Knee Society

Do Fresh Osteochondral Allografts Successfully Treat Femoral Condyle Lesions?

Authors: Yadin D. Levy, MD, Simon Görtz, MD, Pamela A. Pulido, BSN, Julie C. McCauley, MPHc, William D. Bugbee, MD

Published in: Clinical Orthopaedics and Related Research® | Issue 1/2013

Abstract

Background

Fresh osteochondral allograft transplantation is an increasingly common treatment option for chondral and osteochondral lesions in the knee, but the long-term outcome is unknown.

Questions/purposes

We determined (1) pain and function, (2) frequency and types of reoperations, (3) survivorship at a median of 13.5 years, and (4) predictors of osteochondral allograft failure in the distal femur.

Methods

We evaluated 122 patients (129 knees) who underwent osteochondral allograft transplantation of the femoral condyle. Mean age was 33 years and 53% were male. Clinical evaluation included the modified Merle d’Aubigné-Postel (18-point), IKDC, and Knee Society function (KS-F) scores. We defined graft failure as revision osteochondral allografting or conversion to arthroplasty. We determined whether patient characteristics or attributes of the graft influenced failure. Minimum followup was 2.4 years (median, 13.5 years); 91% had more than 10 years of followup.

Results

Mean modified Merle d’Aubigné-Postel score improved from 12.1 to 16, mean IKDC pain score from 7.0 to 3.8, mean IKDC function score from 3.4 to 7.2, and mean KS-F score from 65.6 to 82.5. Sixty-one knees (47%) underwent reoperations. Thirty-one knees (24%) failed at a mean of 7.2 years. Survivorship was 82% at 10 years, 74% at 15 years, and 66% at 20 years. Age of more than 30 years at time of surgery and having two or more previous surgeries for the operated knee were associated with allograft failure.

Conclusions

Followup of femoral condyle osteochondral allografting demonstrated durable improvement in pain and function, with graft survivorship of 82% at 10 years.

Level of Evidence

Level IV, therapeutic study. See the Instructions for Authors for a complete description of levels of evidence.

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Title: Do Fresh Osteochondral Allografts Successfully Treat Femoral Condyle Lesions?
Authors: Yadin D. Levy, MD
Simon Görtz, MD
Pamela A. Pulido, BSN
Julie C. McCauley, MPHc
William D. Bugbee, MD
Publication date: 01-01-2013
Publisher: Springer-Verlag
Published in: Clinical Orthopaedics and Related Research® / Issue 1/2013
Print ISSN: 0009-921X
Electronic ISSN: 1528-1132
DOI: https://doi.org/10.1007/s11999-012-2556-4

ACC 2024 Congress

Springer Medicine

Do Fresh Osteochondral Allografts Successfully Treat Femoral Condyle Lesions?

Abstract

Background

Questions/purposes

Methods

Results

Conclusions

Level of Evidence

ACC 2024 Congress

Springer Medicine

Abstract

Background

Questions/purposes

Methods

Results

Conclusions

Level of Evidence

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