Skip to main content
Top
Published in: Clinical Orthopaedics and Related Research® 4/2011

01-04-2011 | Clinical Research

Factors Influencing Health-related Quality of Life after TKA in Patients who are Obese

Authors: Montserrat Nuñez, PhD, Lluis Lozano, PhD, Esther Nuñez, PhD, Josep-Maria Segur, PhD, Sergi Sastre, PhD

Published in: Clinical Orthopaedics and Related Research® | Issue 4/2011

Login to get access

Abstract

Background

Although the health-related quality of life (HRQL) for patients who are obese seems to improve after TKA, the magnitude of improvement and the associated factors remain controversial. We previously found body mass index was not associated with changes in HRQL after TKA.

Questions/purposes

The purposes of this secondary analysis were to determine which patient characteristics and surgical factors were associated with worse health status after TKA in patients who are severe or morbidly obese.

Methods

We assessed 60 patients (53 females; mean age, 70 years) 12 months after surgery. The mean number of comorbidities was 2.5. Mean lower limb anthropometric index scores were: suprapatellar, 1.6; infrapatellar, 2; and suprapatellar/infrapatellar, 1.2. Intraoperative difficulty (IOD) was Grade 0, 40%; Grade 1, 48%; and Grade 2, 12%. Ten patients (17%) had complications. We measured HRQL using the disease-specific WOMAC questionnaire. Patient characteristics (sociodemographic variables, BMI, comorbidity, lower limb anthropometry) and surgical factors (IOD, complications, postoperative medical data) were collected. Associations between WOMAC dimension scores at 12 months and patient characteristics and surgical factors were analyzed using linear regression models.

Results

Factors associated with worse WOMAC dimension scores in patients who were obese included the number of comorbidities, an infrapatellar index percentile less than 75, IOD Grade 2, and the number of complications after discharge.

Conclusions

For patients with knee osteoarthritis who were severe or morbidly obese, various lower limb anthropometric features, degree of IOD, and postoperative complications negatively influenced postoperative WOMAC scores.

Level of Evidence

Level II Prognostic Study. See Guidelines for a complete description of levels of evidence.
Literature
1.
go back to reference Bellamy N. WOMAC: a 20-year experimental review of a patient-centered self-reported health status questionnaire. J Rheumatol. 2002;29:2473–2476.PubMed Bellamy N. WOMAC: a 20-year experimental review of a patient-centered self-reported health status questionnaire. J Rheumatol. 2002;29:2473–2476.PubMed
2.
go back to reference Deshmukh RG, Hayes JH, Pinder IM. Does body weight influence outcome after total knee arthroplasty? A 1-year analysis. J Arthroplasty. 2002;17:315–319.PubMedCrossRef Deshmukh RG, Hayes JH, Pinder IM. Does body weight influence outcome after total knee arthroplasty? A 1-year analysis. J Arthroplasty. 2002;17:315–319.PubMedCrossRef
3.
go back to reference Escobar A, Quintana JM, Bilbao A, Azkarate J, Guenaga JI. Validation of the Spanish version of the WOMAC questionnaire for patients with hip or knee osteoarthritis: Western Ontario and McMaster Universities Osteoarthritis Index. Clin Rheumatol. 2002;21:466–471.PubMedCrossRef Escobar A, Quintana JM, Bilbao A, Azkarate J, Guenaga JI. Validation of the Spanish version of the WOMAC questionnaire for patients with hip or knee osteoarthritis: Western Ontario and McMaster Universities Osteoarthritis Index. Clin Rheumatol. 2002;21:466–471.PubMedCrossRef
4.
go back to reference Ethgen O, Bruyere O, Richy F, Dardennes C, Reginster JY. Health-related quality of life in total hip and total knee arthroplasty: a qualitative and systematic review of the literature. J Bone Joint Surg Am. 2004;86:963–974.PubMed Ethgen O, Bruyere O, Richy F, Dardennes C, Reginster JY. Health-related quality of life in total hip and total knee arthroplasty: a qualitative and systematic review of the literature. J Bone Joint Surg Am. 2004;86:963–974.PubMed
5.
go back to reference Ethgen O, Vanparijs P, Delhalle S, Rosant S, Bruyere O, Reginster JY. Social support and health-related quality of life in hip and knee osteoarthritis. Qual Life Res. 2004;13:321–330.PubMedCrossRef Ethgen O, Vanparijs P, Delhalle S, Rosant S, Bruyere O, Reginster JY. Social support and health-related quality of life in hip and knee osteoarthritis. Qual Life Res. 2004;13:321–330.PubMedCrossRef
6.
go back to reference Fehring TK, Odum SM, Griffin WL, Mason JB, McCoy TH. The obesity epidemic: its effect on total joint arthroplasty. J Arthroplasty. 2007;22(6 suppl 2):71–76. Fehring TK, Odum SM, Griffin WL, Mason JB, McCoy TH. The obesity epidemic: its effect on total joint arthroplasty. J Arthroplasty. 2007;22(6 suppl 2):71–76.
7.
go back to reference Fisher DA, Dierckman B, Watts MR, Davis K. Looks good but feels bad: factors that contribute to poor results after total knee arthroplasty. J Arthroplasty. 2007;22(6 suppl 2):39–42. Fisher DA, Dierckman B, Watts MR, Davis K. Looks good but feels bad: factors that contribute to poor results after total knee arthroplasty. J Arthroplasty. 2007;22(6 suppl 2):39–42.
8.
go back to reference Foran JR, Mont MA, Rajadhyaksha AD, Jones LC, Etienne G, Hungerford DS. Total knee arthroplasty in obese patients: a comparison with a matched control group. J Arthroplasty. 2004;19:817–824.PubMedCrossRef Foran JR, Mont MA, Rajadhyaksha AD, Jones LC, Etienne G, Hungerford DS. Total knee arthroplasty in obese patients: a comparison with a matched control group. J Arthroplasty. 2004;19:817–824.PubMedCrossRef
9.
go back to reference Franklin PD, Li W, Ayers DC. The Chitranjan Ranawat Award: functional outcome after total knee replacement varies with patient attributes. Clin Orthop Relat Res. 2008;466:2597–2604.PubMedCrossRef Franklin PD, Li W, Ayers DC. The Chitranjan Ranawat Award: functional outcome after total knee replacement varies with patient attributes. Clin Orthop Relat Res. 2008;466:2597–2604.PubMedCrossRef
11.
go back to reference Griffin FM, Scuderi GR, Insall JN, Colizza W. Total knee arthroplasty in patients who were obese with 10 years followup. Clin Orthop Relat Res. 1998;356:28–33.PubMedCrossRef Griffin FM, Scuderi GR, Insall JN, Colizza W. Total knee arthroplasty in patients who were obese with 10 years followup. Clin Orthop Relat Res. 1998;356:28–33.PubMedCrossRef
12.
go back to reference Hawker G, Wright J, Coyte P, Paul J, Dittus R, Croxford R, Katz B, Bombardier C, Heck D, Freund D. Health-related quality of life after knee replacement. J Bone Joint Surg Am. 1998;80:163–173.PubMed Hawker G, Wright J, Coyte P, Paul J, Dittus R, Croxford R, Katz B, Bombardier C, Heck D, Freund D. Health-related quality of life after knee replacement. J Bone Joint Surg Am. 1998;80:163–173.PubMed
13.
go back to reference Jones CA, Beaupre LA, Johnston DW, Suarez-Almazor ME. Total joint arthroplasties: current concepts of patient outcomes after surgery. Rheum Dis Clin North Am. 2007;33:71–86.PubMedCrossRef Jones CA, Beaupre LA, Johnston DW, Suarez-Almazor ME. Total joint arthroplasties: current concepts of patient outcomes after surgery. Rheum Dis Clin North Am. 2007;33:71–86.PubMedCrossRef
14.
go back to reference Jones DL, Westby MD, Greidanus N, Johanson NA, Krebs DE, Robbins L, Rooks DS, Brander V. Update on hip and knee arthroplasty: current state of evidence. Arthritis Rheum. 2005;53:772–780.PubMedCrossRef Jones DL, Westby MD, Greidanus N, Johanson NA, Krebs DE, Robbins L, Rooks DS, Brander V. Update on hip and knee arthroplasty: current state of evidence. Arthritis Rheum. 2005;53:772–780.PubMedCrossRef
15.
go back to reference Kane RL, Saleh KJ, Bershadsky B, Cross WW 3rd, MacDonald RM, Rutks I. Total knee replacement. Evidence Report/Technology Assessment No. 86 (Prepared by Minnesota Evidence-based Practice Center, Minneapolis, Minnesota). AHRQ Publication No. 04-E006-1. Rockville, MD: Agency for Healthcare Research and Quality. November 2003. Available at: http://www.ahrq.gov/clinic/epcsums/kneesum.pdf. Accessed December 2003. Kane RL, Saleh KJ, Bershadsky B, Cross WW 3rd, MacDonald RM, Rutks I. Total knee replacement. Evidence Report/Technology Assessment No. 86 (Prepared by Minnesota Evidence-based Practice Center, Minneapolis, Minnesota). AHRQ Publication No. 04-E006-1. Rockville, MD: Agency for Healthcare Research and Quality. November 2003. Available at: http://​www.​ahrq.​gov/​clinic/​epcsums/​kneesum.​pdf. Accessed December 2003.
16.
go back to reference Kellgren JH, Lawrence JS. Atlas of Standard Radiographs: The Epidemiology of Chronic Rheumatism. Oxford, England: Blackwell Scientific Publications; 1996. Kellgren JH, Lawrence JS. Atlas of Standard Radiographs: The Epidemiology of Chronic Rheumatism. Oxford, England: Blackwell Scientific Publications; 1996.
17.
go back to reference Lozano LM, Nunez M, Segur JM, Macule F, Sastre S, Nunez E, Suso S. Relationship between knee anthropometry and surgical time in total knee arthroplasty in severely and morbidly obese patients: a new prognostic index of surgical difficulty. Obes Surg. 2008;18:1149–1153.PubMedCrossRef Lozano LM, Nunez M, Segur JM, Macule F, Sastre S, Nunez E, Suso S. Relationship between knee anthropometry and surgical time in total knee arthroplasty in severely and morbidly obese patients: a new prognostic index of surgical difficulty. Obes Surg. 2008;18:1149–1153.PubMedCrossRef
18.
go back to reference Lozano LM, Segur JM, Macule F, Nunez M, Torner P, Castillo F, Suso S. Intramedullary versus extramedullary tibial cutting guide in severely obese patients undergoing total knee replacement: a randomized study of 70 patients with body mass index > 35 kg/m2. Obes Surg. 2008;18:1599–1604.PubMedCrossRef Lozano LM, Segur JM, Macule F, Nunez M, Torner P, Castillo F, Suso S. Intramedullary versus extramedullary tibial cutting guide in severely obese patients undergoing total knee replacement: a randomized study of 70 patients with body mass index > 35 kg/m2. Obes Surg. 2008;18:1599–1604.PubMedCrossRef
19.
go back to reference Mason JB. The new demands by patients in the modern era of total joint arthroplasty: a point of view. Clin Orthop Relat Res. 2008;466:146–152.PubMedCrossRef Mason JB. The new demands by patients in the modern era of total joint arthroplasty: a point of view. Clin Orthop Relat Res. 2008;466:146–152.PubMedCrossRef
20.
go back to reference Miric A, Lim M, Kahn B, Rozenthal T, Bombick D, Sculco TP. Perioperative morbidity following total knee arthroplasty among obese patients. J Knee Surg. 2002;15:77–83.PubMed Miric A, Lim M, Kahn B, Rozenthal T, Bombick D, Sculco TP. Perioperative morbidity following total knee arthroplasty among obese patients. J Knee Surg. 2002;15:77–83.PubMed
21.
go back to reference Namba RS, Paxton L, Fithian DC, Stone ML. Obesity and perioperative morbidity in total hip and total knee arthroplasty patients. J Arthroplasty. 2005;20(7 suppl 3):46–50. Namba RS, Paxton L, Fithian DC, Stone ML. Obesity and perioperative morbidity in total hip and total knee arthroplasty patients. J Arthroplasty. 2005;20(7 suppl 3):46–50.
22.
go back to reference Nunez M, Lozano L, Nunez E, Segur JM, Sastre S, Macule F, Ortega R, Suso S. Total knee replacement and health-related quality of life: factors influencing long-term outcomes. Arthritis Rheum. 2009;61:1062–1069.PubMedCrossRef Nunez M, Lozano L, Nunez E, Segur JM, Sastre S, Macule F, Ortega R, Suso S. Total knee replacement and health-related quality of life: factors influencing long-term outcomes. Arthritis Rheum. 2009;61:1062–1069.PubMedCrossRef
23.
go back to reference Nunez M, Nunez E, del Val JL, Ortega R, Segur JM, Hernandez MV, Lozano L, Sastre S, Macule F. Health-related quality of life in patients with osteoarthritis after total knee replacement: factors influencing outcomes at 36 months of follow-up. Osteoarthritis Cartilage. 2007;15:1001–1007.PubMedCrossRef Nunez M, Nunez E, del Val JL, Ortega R, Segur JM, Hernandez MV, Lozano L, Sastre S, Macule F. Health-related quality of life in patients with osteoarthritis after total knee replacement: factors influencing outcomes at 36 months of follow-up. Osteoarthritis Cartilage. 2007;15:1001–1007.PubMedCrossRef
24.
go back to reference Nunez M, Nunez E, Segur JM, Macule F, Quinto L, Hernandez MV, Vilalta C. The effect of an educational program to improve health-related quality of life in patients with osteoarthritis on waiting list for total knee replacement: a randomized study. Osteoarthritis Cartilage. 2006;14:279–285.PubMedCrossRef Nunez M, Nunez E, Segur JM, Macule F, Quinto L, Hernandez MV, Vilalta C. The effect of an educational program to improve health-related quality of life in patients with osteoarthritis on waiting list for total knee replacement: a randomized study. Osteoarthritis Cartilage. 2006;14:279–285.PubMedCrossRef
25.
go back to reference Peersman G, Laskin R, Davis J, Peterson M: Infection in total knee replacement: a retrospective review of 6489 total knee replacements. Clin Orthop Relat Res. 2001;392:15–23.PubMedCrossRef Peersman G, Laskin R, Davis J, Peterson M: Infection in total knee replacement: a retrospective review of 6489 total knee replacements. Clin Orthop Relat Res. 2001;392:15–23.PubMedCrossRef
27.
go back to reference Rajgopal V, Bourne RB, Chesworth BM, MacDonald SJ, McCalden RW, Rorabeck CH. The impact of morbid obesity on patient outcomes after total knee arthroplasty. J Arthroplasty. 2008;23:795–800.PubMedCrossRef Rajgopal V, Bourne RB, Chesworth BM, MacDonald SJ, McCalden RW, Rorabeck CH. The impact of morbid obesity on patient outcomes after total knee arthroplasty. J Arthroplasty. 2008;23:795–800.PubMedCrossRef
28.
go back to reference Santaguida PL, Hawker GA, Hudak PL, Glazier R, Mahomed NN, Kreder HJ, Coyte PC, Wright JG: Patient characteristics affecting the prognosis of total hip and knee joint arthroplasty: a systematic review. Can J Surg. 2008;51:428–436. Santaguida PL, Hawker GA, Hudak PL, Glazier R, Mahomed NN, Kreder HJ, Coyte PC, Wright JG: Patient characteristics affecting the prognosis of total hip and knee joint arthroplasty: a systematic review. Can J Surg. 2008;51:428–436.
29.
go back to reference Singh J, Sloan JA, Johanson NA. Challenges with health-related quality of life assessment in arthroplasty patients: problems and solutions. J Am Acad Orthop Surg. 2010;18:72–82.PubMed Singh J, Sloan JA, Johanson NA. Challenges with health-related quality of life assessment in arthroplasty patients: problems and solutions. J Am Acad Orthop Surg. 2010;18:72–82.PubMed
30.
go back to reference Spicer DD, Schaper LA, Pomeroy DL, Badenhausen WE Jr, Curry JI, Suthers KE, Smith MW. Cementless cup fixation in total hip arthroplasty after 5-8 years. Int Orthop. 2001; 25:286–289.PubMedCrossRef Spicer DD, Schaper LA, Pomeroy DL, Badenhausen WE Jr, Curry JI, Suthers KE, Smith MW. Cementless cup fixation in total hip arthroplasty after 5-8 years. Int Orthop. 2001; 25:286–289.PubMedCrossRef
31.
go back to reference Whiteside LA, Nakamura T. Effect of femoral component design on unresurfaced patellas in knee arthroplasty. Clin Orthop Relat Res. 2003;410:189–198.PubMedCrossRef Whiteside LA, Nakamura T. Effect of femoral component design on unresurfaced patellas in knee arthroplasty. Clin Orthop Relat Res. 2003;410:189–198.PubMedCrossRef
32.
go back to reference Winiarsky R, Barth P, Lotke P. Total knee arthroplasty in morbidly obese patients. J Bone Joint Surg Am. 1998;80:1770–1774.PubMed Winiarsky R, Barth P, Lotke P. Total knee arthroplasty in morbidly obese patients. J Bone Joint Surg Am. 1998;80:1770–1774.PubMed
33.
go back to reference World Health Organization. Obesity: preventing and managing the global epidemic. Report of a WHO Consultation.WHO Technical Report Series. No. 894. Geneva, Switzerland: World Health Organization; 2000. World Health Organization. Obesity: preventing and managing the global epidemic. Report of a WHO Consultation.WHO Technical Report Series. No. 894. Geneva, Switzerland: World Health Organization; 2000.
Metadata
Title
Factors Influencing Health-related Quality of Life after TKA in Patients who are Obese
Authors
Montserrat Nuñez, PhD
Lluis Lozano, PhD
Esther Nuñez, PhD
Josep-Maria Segur, PhD
Sergi Sastre, PhD
Publication date
01-04-2011
Publisher
Springer-Verlag
Published in
Clinical Orthopaedics and Related Research® / Issue 4/2011
Print ISSN: 0009-921X
Electronic ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-010-1671-3

Other articles of this Issue 4/2011

Clinical Orthopaedics and Related Research® 4/2011 Go to the issue

Symposium: Periprosthetic Joint Infection

Biographical Sketch: William S. Baer (1872–1931)

Symposium: Periprosthetic Joint Infection

Periprosthetic Joint Infection: Editorial Comment