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Current Urology Reports
Published in: Current Urology Reports 6/2011

01-12-2011 | Overactive Bladder (Gopal Badlani, Section Editor)

Bladder Dysfunction and Parkinsonism: Current Pathophysiological Understanding and Management Strategies

Authors: Lysanne Campeau, Roberto Soler, Karl-Erik Andersson

Published in: Current Urology Reports | Issue 6/2011

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Abstract

Patients with Parkinson’s disease (PD) commonly develop lower urinary tract symptoms (LUTS) as their disease severity progresses. It is a well-established fact that neurodegeneration of the nigrostriatal dopaminergic pathway occurs in PD. This neurochemical deficiency explains many of the motor disturbances encountered in patients with PD. However, the underlying cause of urinary dysfunction present in over half of patients with PD is poorly understood. Without clearly understanding the underlying pathophysiological and neurochemical mechanisms of LUTS associated with PD, treatment strategies are mainly empirical in nature. This review presents the most recent studies and evidence on the pathophysiological mechanisms of PD-related voiding dysfunction and its available therapies.
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Metadata
Title
Bladder Dysfunction and Parkinsonism: Current Pathophysiological Understanding and Management Strategies
Authors
Lysanne Campeau
Roberto Soler
Karl-Erik Andersson
Publication date
01-12-2011
Publisher
Current Science Inc.
Published in
Current Urology Reports / Issue 6/2011
Print ISSN: 1527-2737
Electronic ISSN: 1534-6285
DOI
https://doi.org/10.1007/s11934-011-0219-8

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