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Published in: Current Urology Reports 6/2011

01-12-2011 | Erectile Dysfunction (Tom Lue, Section Editor)

Emerging and Novel Therapeutic Approaches in the Treatment of Male Erectile Dysfunction

Authors: Eric Chung, Gerald B. Brock

Published in: Current Urology Reports | Issue 6/2011

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Abstract

Over the past few decades, a dramatic increase in our understanding of the pathophysiology of penile erection has occurred. The advent of phosphodiesterase type 5 inhibitors has revolutionized the treatment of erectile dysfunction (ED), while the introduction of modern penile prosthesis has almost completely replaced the need for vascular surgery. Despite the efficacy of current therapeutic options for ED, they are not without limitations and remain insufficient to address the growing patient population and various underlying medical conditions. Newer and novel ED therapies aspire to treat underlying microvascular abnormalities, prevent cavernosal fibrosis, promote endothelial revascularization, modulate neurohormonal pathways, and regenerate new penile tissue.
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Metadata
Title
Emerging and Novel Therapeutic Approaches in the Treatment of Male Erectile Dysfunction
Authors
Eric Chung
Gerald B. Brock
Publication date
01-12-2011
Publisher
Current Science Inc.
Published in
Current Urology Reports / Issue 6/2011
Print ISSN: 1527-2737
Electronic ISSN: 1534-6285
DOI
https://doi.org/10.1007/s11934-011-0216-y

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