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Current Rheumatology Reports
Published in: Current Rheumatology Reports 4/2015

01-04-2015 | Vasculitis (LR Espinoza, Section Editor)

Cogan’s Syndrome and Other Ocular Vasculitides

Authors: Gabriela M. Espinoza, Angela Prost

Published in: Current Rheumatology Reports | Issue 4/2015

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Abstract

The clinical presentation of Cogan’s syndrome has been classified as typical and atypical. Like other forms of ocular vasculitis, Cogan’s syndrome has been found to have autoimmune origins with antibodies against the cornea, inner ear, and endothelial antigens. Antineutrophil cytoplasmic antibody (ANCA) and rheumatoid factor (RF) have been associated with Cogan’s syndrome as well as ocular-involving vasculitides not as strongly associated with the audiovestibular manifestations such as granulomatosis with polyangiitis and rheumatoid arthritis. The mainstay of therapy has been corticosteroids although other methods have been described in recalcitrant disease and to prevent development of systemic sequelae.
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Metadata
Title
Cogan’s Syndrome and Other Ocular Vasculitides
Authors
Gabriela M. Espinoza
Angela Prost
Publication date
01-04-2015
Publisher
Springer US
Published in
Current Rheumatology Reports / Issue 4/2015
Print ISSN: 1523-3774
Electronic ISSN: 1534-6307
DOI
https://doi.org/10.1007/s11926-015-0499-y

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