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Published in: Current Rheumatology Reports 9/2014

01-09-2014 | SPONDYLOARTHRITIS (MA KHAN, SECTION EDITOR)

Seronegative Arthritis in Latin America: A Current Review

Authors: Carla Gonçalves Schain Saad, Célio Roberto Gonçalves, Percival D. Sampaio-Barros

Published in: Current Rheumatology Reports | Issue 9/2014

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Abstract

In many Latin American countries seronegative arthritis, especially the spondyloarthritides (SpA), is commonly characterized by associated axial and peripheral involvement. In this article, the authors review the ethnic distribution of the population and the different SpA in 10 Latin American countries, and the main characteristics of the Ibero-American Registry of Spondyloarthropathies (RESPONDIA) compared with other international registries. The peripheral component of SpA is more frequent in mixed-race populations, whereas psoriatic arthritis is significantly more frequent in countries with predominantly white populations.
Literature
1.
go back to reference Espinoza LR, Toloza SM, Valle-Onate R, Mease PJ. Global partnering opportunities and challenges of psoriasis and psoriatic arthritis in Latin America: a report from the GRAPPA 2010 annual meeting. J Rheumatol. 2012;39:445–7.PubMedCrossRef Espinoza LR, Toloza SM, Valle-Onate R, Mease PJ. Global partnering opportunities and challenges of psoriasis and psoriatic arthritis in Latin America: a report from the GRAPPA 2010 annual meeting. J Rheumatol. 2012;39:445–7.PubMedCrossRef
2.•
go back to reference Benegas M, Muñoz-Gomariz E, Font P, Burgos-Vargas R, Chaves J, Palleiro D, et al. Comparison of the clinical expression of patients with ankylosing spondylitis from Europe and Latin America. J Rheumatol. 2012;39:2315–20. This article, comparing 1,083 Latin American (from nine countries) and 2,356 European patients (from Spain and Belgium), shows that the Latin American patients were characterized by a higher frequency of peripheral involvement and enthesitis whereas the European patients had a significantly higher percentage of positive HLA-B27.PubMedCrossRef Benegas M, Muñoz-Gomariz E, Font P, Burgos-Vargas R, Chaves J, Palleiro D, et al. Comparison of the clinical expression of patients with ankylosing spondylitis from Europe and Latin America. J Rheumatol. 2012;39:2315–20. This article, comparing 1,083 Latin American (from nine countries) and 2,356 European patients (from Spain and Belgium), shows that the Latin American patients were characterized by a higher frequency of peripheral involvement and enthesitis whereas the European patients had a significantly higher percentage of positive HLA-B27.PubMedCrossRef
3.
go back to reference Vander Cruyssen B, Muñoz-Gomariz E, Font P, Mulero J, de Vlam K, Boonen A, et al. Hip involvement in ankylosing spondylitis: epidemiology and risk factors associated with hip replacement surgery. Rheumatology (Oxford). 2010;49:73–81.CrossRef Vander Cruyssen B, Muñoz-Gomariz E, Font P, Mulero J, de Vlam K, Boonen A, et al. Hip involvement in ankylosing spondylitis: epidemiology and risk factors associated with hip replacement surgery. Rheumatology (Oxford). 2010;49:73–81.CrossRef
4.
go back to reference Pérez Alamino R, Maldonado Cocco JA, Citera G, Arturi P, Vazquez-Mellado J, Sampaio-Barros PD, et al. Differential features between primary ankylosing spondylitis and spondylitis associated with psoriasis and inflammatory disease. J Rheumatol. 2011;38:1656–60.PubMedCrossRef Pérez Alamino R, Maldonado Cocco JA, Citera G, Arturi P, Vazquez-Mellado J, Sampaio-Barros PD, et al. Differential features between primary ankylosing spondylitis and spondylitis associated with psoriasis and inflammatory disease. J Rheumatol. 2011;38:1656–60.PubMedCrossRef
5.
go back to reference Sampaio-Barros PD, Pereira IA, Hernández-Cuevas C, Berman A, Burgos-Vargas R, Gutierrez MA, et al. An analysis of 372 patients with anterior uveitis in a large Ibero-American cohort of spondyloarthritis: the RESPONDIA group. Clin Exp Rheumatol. 2013;31:484–9.PubMed Sampaio-Barros PD, Pereira IA, Hernández-Cuevas C, Berman A, Burgos-Vargas R, Gutierrez MA, et al. An analysis of 372 patients with anterior uveitis in a large Ibero-American cohort of spondyloarthritis: the RESPONDIA group. Clin Exp Rheumatol. 2013;31:484–9.PubMed
6.
go back to reference Gallinaro AL, Ventura C, Sampaio Barros PD, Gonçalves CR. Spondyloarthritis: analysis of a Brazilian series compared with a large Ibero-American registry (RESPONDIA group). Braz J Rheumatol. 2010;50:581–9. Gallinaro AL, Ventura C, Sampaio Barros PD, Gonçalves CR. Spondyloarthritis: analysis of a Brazilian series compared with a large Ibero-American registry (RESPONDIA group). Braz J Rheumatol. 2010;50:581–9.
7.
go back to reference Buschiazzo E, Maldonado-Cocco JA, Arturi P, Citera G, Berman A, Nitsche A, et al. Epidemiology of spondyloarthritis in Argentina. Am J Med Sci. 2011;341:289–92.PubMedCrossRef Buschiazzo E, Maldonado-Cocco JA, Arturi P, Citera G, Berman A, Nitsche A, et al. Epidemiology of spondyloarthritis in Argentina. Am J Med Sci. 2011;341:289–92.PubMedCrossRef
8.
go back to reference Soriano ER, Rosa J, Velozo E, Schpilberg M, Imamura PM, Diaz J. Incidence and prevalence of psoriatic arthritis in Buenos Aires, Argentina: a 6-year health management organization-based study. Rheumatology (Oxford). 2011;50:729–34.CrossRef Soriano ER, Rosa J, Velozo E, Schpilberg M, Imamura PM, Diaz J. Incidence and prevalence of psoriatic arthritis in Buenos Aires, Argentina: a 6-year health management organization-based study. Rheumatology (Oxford). 2011;50:729–34.CrossRef
9.
go back to reference Arturi P, Schneeberger EE, Sommerfleck F, Buschiazzo E, Ledesma C, Maldonado Cocco JA, et al. Adherence to treatment in patients with ankylosing spondylitis. Clin Rheumatol. 2013;32:1007–15.PubMedCrossRef Arturi P, Schneeberger EE, Sommerfleck F, Buschiazzo E, Ledesma C, Maldonado Cocco JA, et al. Adherence to treatment in patients with ankylosing spondylitis. Clin Rheumatol. 2013;32:1007–15.PubMedCrossRef
10.
go back to reference Skare TL, Bortoluzzo AB, Gonçalves CR, Braga da Silva JA, Ximenes AC, Bértolo MB, et al. Ethnic influence in clinical and functional measures of Brazilian patients with spondyloarthritis. J Rheumatol. 2012;39:141–7.PubMedCrossRef Skare TL, Bortoluzzo AB, Gonçalves CR, Braga da Silva JA, Ximenes AC, Bértolo MB, et al. Ethnic influence in clinical and functional measures of Brazilian patients with spondyloarthritis. J Rheumatol. 2012;39:141–7.PubMedCrossRef
11.
go back to reference de Carvalho HM, Bortoluzzo AB, Gonçalves CR, da Silva JA, Ximenes AC, Bértolo MB, et al. Gender characterization in a large series of Brazilian patients with spondyloarthritis. Clin Rheumatol. 2012;31:687–95.PubMedCrossRef de Carvalho HM, Bortoluzzo AB, Gonçalves CR, da Silva JA, Ximenes AC, Bértolo MB, et al. Gender characterization in a large series of Brazilian patients with spondyloarthritis. Clin Rheumatol. 2012;31:687–95.PubMedCrossRef
12.
go back to reference Skare TL, Leite N, Bortoluzzo AB, Gonçalves CR, da Silva JA, Ximenes AC, et al. Effect of age at disease onset in the clinical profile of spondyloarthritis: a study of 1424 Brazilian patients. Clin Exp Rheumatol. 2012;30:351–7.PubMed Skare TL, Leite N, Bortoluzzo AB, Gonçalves CR, da Silva JA, Ximenes AC, et al. Effect of age at disease onset in the clinical profile of spondyloarthritis: a study of 1424 Brazilian patients. Clin Exp Rheumatol. 2012;30:351–7.PubMed
13.•
go back to reference Carneiro S, Bortoluzzo AB, Gonçalves CR, da Silva JA, Ximenes AC, Bértolo MB, et al. Effect of enthesitis on 1505 Brazilian patients with spondyloarthritis. J Rheumatol. 2013;40:1719–25. This article reveals that when the MASES was applied to a group of 1,505 Brazilian patients with SpA, 54 % had at least one affected enthesis. Achilles enthesitis also was associated with work incapacity in the multivariate logistic regression analysis.PubMedCrossRef Carneiro S, Bortoluzzo AB, Gonçalves CR, da Silva JA, Ximenes AC, Bértolo MB, et al. Effect of enthesitis on 1505 Brazilian patients with spondyloarthritis. J Rheumatol. 2013;40:1719–25. This article reveals that when the MASES was applied to a group of 1,505 Brazilian patients with SpA, 54 % had at least one affected enthesis. Achilles enthesitis also was associated with work incapacity in the multivariate logistic regression analysis.PubMedCrossRef
14.
go back to reference Bonfiglioli R, Carneiro S, Bortoluzzo AB, Gonçalves CR, da Silva JA, Ximenes AC, et al. Characteristics of psoriatic arthritis in a large cohort of Brazilian patients with spondyloarthritis. Braz J Rheumatol. 2014; submitted to publication. Bonfiglioli R, Carneiro S, Bortoluzzo AB, Gonçalves CR, da Silva JA, Ximenes AC, et al. Characteristics of psoriatic arthritis in a large cohort of Brazilian patients with spondyloarthritis. Braz J Rheumatol. 2014; submitted to publication.
15.
go back to reference Favarato MH, Mease P, Gonçalves CR, Gonçalves Saad C, Sampaio-Barros PD, Goldenstein-Schainberg C. Hypertension and diabetes significantly enhance the risk of cardiovascular disease in patients with psoriatic arthritis. Clin Exp Rheumatol. 2014; 32:182–7. Favarato MH, Mease P, Gonçalves CR, Gonçalves Saad C, Sampaio-Barros PD, Goldenstein-Schainberg C. Hypertension and diabetes significantly enhance the risk of cardiovascular disease in patients with psoriatic arthritis. Clin Exp Rheumatol. 2014; 32:182–7.
16.
go back to reference Lanna CC, Ferrari ML, Rocha SL, Nascimento E, de Carvalho MM, da Cunha AS. A cross-sectional study of 130 Brazilian patients with Crohn’s disease and ulcerative colitis: analysis of articular and ophthalmologic manifestations. Clin Rheumatol. 2008;27:503–9.PubMedCrossRef Lanna CC, Ferrari ML, Rocha SL, Nascimento E, de Carvalho MM, da Cunha AS. A cross-sectional study of 130 Brazilian patients with Crohn’s disease and ulcerative colitis: analysis of articular and ophthalmologic manifestations. Clin Rheumatol. 2008;27:503–9.PubMedCrossRef
17.
go back to reference Resende GG, Lanna CC, Bortoluzzo AB, Gonçalves CR, Braga da Silva JA, Ximenes AC, et al. Enteropathic arthritis in Brazil: data from the Brazilian Registry of Spondyloarthritis. Braz J Rheumatol. 2013;53:452–6. Resende GG, Lanna CC, Bortoluzzo AB, Gonçalves CR, Braga da Silva JA, Ximenes AC, et al. Enteropathic arthritis in Brazil: data from the Brazilian Registry of Spondyloarthritis. Braz J Rheumatol. 2013;53:452–6.
18.
go back to reference Sampaio-Barros PD, Bortoluzzo AB, Conde RA, Costallat LT, Samara AM, Bértolo MB. Undifferentiated spondyloarthritis: a long-term follow-up. J Rheumatol. 2010;37:1195–9.PubMedCrossRef Sampaio-Barros PD, Bortoluzzo AB, Conde RA, Costallat LT, Samara AM, Bértolo MB. Undifferentiated spondyloarthritis: a long-term follow-up. J Rheumatol. 2010;37:1195–9.PubMedCrossRef
19.
go back to reference Lage RC, Bomtempo CAS, Kakehasi AM, de Carvalho MA. Undifferentiated spondyloarthritis in a heterogeneous Brazilian population: an eight-year follow-up study. Rheumatol Int. 2013 Jun 14 (E-pub ahead of print). Lage RC, Bomtempo CAS, Kakehasi AM, de Carvalho MA. Undifferentiated spondyloarthritis in a heterogeneous Brazilian population: an eight-year follow-up study. Rheumatol Int. 2013 Jun 14 (E-pub ahead of print).
20.
go back to reference Sampaio-Barros PD, Santiago MB, Bortoluzzo AB, Ximenes AC, Braga da Silva JA, Bértolo MB, et al. Combined axial and peripheral involvement is associated with miscegenation in a large and heterogenoeus Brazilian cohort of 1505 patients with spondyloarthritis. Arthritis Rheum. 2013;65:S1056. Sampaio-Barros PD, Santiago MB, Bortoluzzo AB, Ximenes AC, Braga da Silva JA, Bértolo MB, et al. Combined axial and peripheral involvement is associated with miscegenation in a large and heterogenoeus Brazilian cohort of 1505 patients with spondyloarthritis. Arthritis Rheum. 2013;65:S1056.
21.
go back to reference Saad CG, Ribeiro AC, Moraes JC, Takayama L, Gonçalves CR, Rodrigues MB, et al. Low sclerostin levels: a predictive marker of persistent inflammation in ankylosing spondylitis during anti-tumor necrosis factor therapy? Arthritis Res Ther. 2012;14:R216.PubMedCrossRefPubMedCentral Saad CG, Ribeiro AC, Moraes JC, Takayama L, Gonçalves CR, Rodrigues MB, et al. Low sclerostin levels: a predictive marker of persistent inflammation in ankylosing spondylitis during anti-tumor necrosis factor therapy? Arthritis Res Ther. 2012;14:R216.PubMedCrossRefPubMedCentral
22.
go back to reference Sampaio-Barros PD, Keiserman M, Meirelles ES, Pinheiro MM, Ximenes AC, Azevedo VF, et al. Recommendations for the management and treatment of ankylosing spondylitis. Braz J Rheumatol. 2013;53:242–57. Sampaio-Barros PD, Keiserman M, Meirelles ES, Pinheiro MM, Ximenes AC, Azevedo VF, et al. Recommendations for the management and treatment of ankylosing spondylitis. Braz J Rheumatol. 2013;53:242–57.
23.
go back to reference Carneiro S, Azevedo VF, Bonfiglioli R, Ranza R, Gonçalves CR, Keiserman M, et al. Recommendations for the management and treatment of psoriatic arthritis. Braz J Rheumatol. 2013;53:227–41. Carneiro S, Azevedo VF, Bonfiglioli R, Ranza R, Gonçalves CR, Keiserman M, et al. Recommendations for the management and treatment of psoriatic arthritis. Braz J Rheumatol. 2013;53:227–41.
24.
go back to reference Gutierrez MA, Pérez C, Saavedra J, Silva F, Fuentealba C, Pozo P, et al. Registro Iberoamericano de Espondiloartritis: Chile. Reumatol Clin. 2008;4 Suppl 4:S41–7. Gutierrez MA, Pérez C, Saavedra J, Silva F, Fuentealba C, Pozo P, et al. Registro Iberoamericano de Espondiloartritis: Chile. Reumatol Clin. 2008;4 Suppl 4:S41–7.
25.
go back to reference Valenzuela F, Silva P, Valdés MP, Papp K. Epidemiology and quality of life of patients with psoriasis in Chile. Actas Dermosifiliogr. 2011;102:810–6.PubMedCrossRef Valenzuela F, Silva P, Valdés MP, Papp K. Epidemiology and quality of life of patients with psoriasis in Chile. Actas Dermosifiliogr. 2011;102:810–6.PubMedCrossRef
26.
go back to reference Valle-Oñate R, Candia L, Romero-Sánchez C, Iglesias-Gamarra A, Caballero-Uribe CV, Santos-Moreno P, et al. Epidemiology of spondyloarthritis in Colombia. Am J Med Sci. 2011;341:293–4.PubMedCrossRef Valle-Oñate R, Candia L, Romero-Sánchez C, Iglesias-Gamarra A, Caballero-Uribe CV, Santos-Moreno P, et al. Epidemiology of spondyloarthritis in Colombia. Am J Med Sci. 2011;341:293–4.PubMedCrossRef
27.
go back to reference Romero-Sánchez C, Londoño J, Delgado G, Jaimes DA, De Avila J, Mora A, et al. Association of tumor necrosis factor alpha-308 promoter polymorphism with spondyloarthritides patients in Colombia. Rheumatol Int. 2012;32:2195–7.PubMedCrossRef Romero-Sánchez C, Londoño J, Delgado G, Jaimes DA, De Avila J, Mora A, et al. Association of tumor necrosis factor alpha-308 promoter polymorphism with spondyloarthritides patients in Colombia. Rheumatol Int. 2012;32:2195–7.PubMedCrossRef
28.
go back to reference Londoño J, Romero-Sanchez MC, Torres VG, Bautista WA, Fernandez DJ, Quiroga JA, et al. The association between serum levels of potential biomarkers with the presence of factors related to the clinical activity and poor prognosis in spondyloarthritis. Braz J Rheumatol. 2012;52:536–44. Londoño J, Romero-Sanchez MC, Torres VG, Bautista WA, Fernandez DJ, Quiroga JA, et al. The association between serum levels of potential biomarkers with the presence of factors related to the clinical activity and poor prognosis in spondyloarthritis. Braz J Rheumatol. 2012;52:536–44.
29.
go back to reference Romero-Sánchez C, Robinson WH, Tomooka BH, Londoño J, Valle-Oñate R, Huang F, et al. Identification of acute phase reactants and cytokines useful for monitoring infliximab therapy in ankylosing spondylitis. Clin Rheumatol. 2008;27:1429–35.PubMedCrossRef Romero-Sánchez C, Robinson WH, Tomooka BH, Londoño J, Valle-Oñate R, Huang F, et al. Identification of acute phase reactants and cytokines useful for monitoring infliximab therapy in ankylosing spondylitis. Clin Rheumatol. 2008;27:1429–35.PubMedCrossRef
30.
go back to reference Saenz-Castro R. Registro Iberoamericano de Espondiloartritis: Costa Rica. Reumatol Clin. 2008;4 Suppl 4:S36–40. Saenz-Castro R. Registro Iberoamericano de Espondiloartritis: Costa Rica. Reumatol Clin. 2008;4 Suppl 4:S36–40.
31.
go back to reference Garcia-Kutzbach A, Montenegro A, Iraheta I, Bará C, Saenz R. Epidemiology of spondyloarthropathies in Central America. Am J Med Sci. 2011;341:295–7.PubMedCrossRef Garcia-Kutzbach A, Montenegro A, Iraheta I, Bará C, Saenz R. Epidemiology of spondyloarthropathies in Central America. Am J Med Sci. 2011;341:295–7.PubMedCrossRef
32.•
go back to reference Peláez-Ballestas I, Navarro-Zarza JE, Julian J, Lopez A, Flores-Camacho R, Casasola-Vargas JC, et al. A community-based study on the prevalence of spondyloarthritis and inflammatory back pain in Mexicans. J Clin Rheumatol. 2013;19:57–61. This study analyzed the results of a door-to-door nurse survey applying the Community Oriented Program for the Control of Rheumatic Diseases (COPCORD) to 4,059 individuals in Mexico City. The prevalence of back pain was 14.6 %, whereas the prevalence of inflammatory back pain was 1.3 % and that of AS was 0.6 %.PubMedCrossRef Peláez-Ballestas I, Navarro-Zarza JE, Julian J, Lopez A, Flores-Camacho R, Casasola-Vargas JC, et al. A community-based study on the prevalence of spondyloarthritis and inflammatory back pain in Mexicans. J Clin Rheumatol. 2013;19:57–61. This study analyzed the results of a door-to-door nurse survey applying the Community Oriented Program for the Control of Rheumatic Diseases (COPCORD) to 4,059 individuals in Mexico City. The prevalence of back pain was 14.6 %, whereas the prevalence of inflammatory back pain was 1.3 % and that of AS was 0.6 %.PubMedCrossRef
33.
go back to reference Burgos-Vargas R, Peláez-Ballestas I. Epidemiology of spondyloarthritis in Mexico. Am J Med Sci. 2011;341:298–300.PubMedCrossRef Burgos-Vargas R, Peláez-Ballestas I. Epidemiology of spondyloarthritis in Mexico. Am J Med Sci. 2011;341:298–300.PubMedCrossRef
34.
go back to reference Huerta-Sil G, Casasola-Vargas JC, Londoño JD, et al. Low-grade radiographic sacroiliitis as prognostic factor in patients with undifferentiated spondyloarthritis fulfilling diagnostic criteria for ankylosing spondylitis throughout follow up. Ann Rheum Dis. 2003;65:642–6.CrossRef Huerta-Sil G, Casasola-Vargas JC, Londoño JD, et al. Low-grade radiographic sacroiliitis as prognostic factor in patients with undifferentiated spondyloarthritis fulfilling diagnostic criteria for ankylosing spondylitis throughout follow up. Ann Rheum Dis. 2003;65:642–6.CrossRef
35.
go back to reference Chavez-Corrales JE, Jauregui MM, Linares MA, Mora C, Valencia PR, Garcia E, et al. Registro Iberoamericano de Espondiloartritis: Peru. Reumatol Clin. 2008;4 Suppl 4:S63–7. Chavez-Corrales JE, Jauregui MM, Linares MA, Mora C, Valencia PR, Garcia E, et al. Registro Iberoamericano de Espondiloartritis: Peru. Reumatol Clin. 2008;4 Suppl 4:S63–7.
36.
go back to reference Toloza SM, Vega-Hinojosa O, Chandran V, Valle-Onate R, Espinoza LR. Psoriasis and psoriatic arthritis in Peruvian aborigines: a report from the GRAPPA 2011 annual meeting. J Rheumatol. 2012;39:2216–9.PubMedCrossRef Toloza SM, Vega-Hinojosa O, Chandran V, Valle-Onate R, Espinoza LR. Psoriasis and psoriatic arthritis in Peruvian aborigines: a report from the GRAPPA 2011 annual meeting. J Rheumatol. 2012;39:2216–9.PubMedCrossRef
37.
go back to reference Palleiro D, Spangenberg E. Registro Iberoamericano de Espondiloartritis (RESPONDIA): Uruguay. Reumatol Clin. 2008;4 (Suppl 4):S73–8. Palleiro D, Spangenberg E. Registro Iberoamericano de Espondiloartritis (RESPONDIA): Uruguay. Reumatol Clin. 2008;4 (Suppl 4):S73–8.
38.
go back to reference Chacón R, Granados Y, Esteva MH, Martinez Y, Maldonado T, Rondón J, et al. Registro Iberoamericano de Espondiloartritis (RESPONDIA): Venezuela. Reumatol Clin. 2008;4 (Suppl 4):S79–86. Chacón R, Granados Y, Esteva MH, Martinez Y, Maldonado T, Rondón J, et al. Registro Iberoamericano de Espondiloartritis (RESPONDIA): Venezuela. Reumatol Clin. 2008;4 (Suppl 4):S79–86.
Metadata
Title
Seronegative Arthritis in Latin America: A Current Review
Authors
Carla Gonçalves Schain Saad
Célio Roberto Gonçalves
Percival D. Sampaio-Barros
Publication date
01-09-2014
Publisher
Springer US
Published in
Current Rheumatology Reports / Issue 9/2014
Print ISSN: 1523-3774
Electronic ISSN: 1534-6307
DOI
https://doi.org/10.1007/s11926-014-0438-3

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