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Published in: Current Rheumatology Reports 2/2013

01-02-2013 | CRYSTAL ARTHRITIS (MH PILLINGER, SECTION EDITOR)

Racial and Gender Disparities Among Patients with Gout

Author: Jasvinder A. Singh

Published in: Current Rheumatology Reports | Issue 2/2013

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Abstract

Gout affects 8.3 million Americans according to NHANES 2007–2008, approximately 3.9 % of the US population. Gout has substantial effect on physical function, productivity, health-related quality of life (HRQOL), and health care costs. Uncontrolled gout is also associated with significant use of emergency care services. Women are less likely to have gout than men, but in the postmenopausal years the gender difference in disease incidence decreases. Compared with whites, racial and/or ethnic minorities, especially blacks, have higher prevalence of gout. Blacks are also less likely to receive quality gout care, leading to disproportionate morbidity. Women are less likely than men to receive allopurinol, and less likely to undergo joint aspirations for crystal analysis to establish diagnosis, but those on urate-lowering therapy are as likely as, or more likely than, men to undergo serum urate check within six months of initiation. Although a few studies provide the knowledge related to gender and race and/or ethnicity disparities for gout, several knowledge gaps exist in gout epidemiology and outcomes differences by gender and race and/or ethnicity. These should be investigated in future studies.
Literature
1.
go back to reference Kimball MM, Neal D, Waters MF, Hoh BL. Race and income disparity in ischemic stroke care: nationwide inpatient sample database, 2002 to 2008. J Stroke Cerebrovasc Dis Off J Natl Stroke Assoc. Jul 17 2012 Kimball MM, Neal D, Waters MF, Hoh BL. Race and income disparity in ischemic stroke care: nationwide inpatient sample database, 2002 to 2008. J Stroke Cerebrovasc Dis Off J Natl Stroke Assoc. Jul 17 2012
2.
go back to reference Wellons MF, Fujimoto VY, Baker VL, et al. Race matters: a systematic review of racial and/or ethnic disparity in Society for Assisted Reproductive Technology reported outcomes. Fertil Steril. 2012;98(2):406–9.PubMedCrossRef Wellons MF, Fujimoto VY, Baker VL, et al. Race matters: a systematic review of racial and/or ethnic disparity in Society for Assisted Reproductive Technology reported outcomes. Fertil Steril. 2012;98(2):406–9.PubMedCrossRef
3.
go back to reference Sclar DA, Robison LM, Schmidt JM, Bowen KA, Castillo LV, Oganov AM. Diagnosis of depression and use of antidepressant pharmacotherapy among adults in the United States: does a disparity persist by ethnicity/race? Clin Drug Investig. 2012;32(2):139–44.PubMedCrossRef Sclar DA, Robison LM, Schmidt JM, Bowen KA, Castillo LV, Oganov AM. Diagnosis of depression and use of antidepressant pharmacotherapy among adults in the United States: does a disparity persist by ethnicity/race? Clin Drug Investig. 2012;32(2):139–44.PubMedCrossRef
4.
go back to reference Kreatsoulas C, Anand SS. Disparity in outcomes of surgical revascularization for limb salvage. Race and gender are synergistic determinants of vein graft failure and limb loss. Nguyen LL, Hevelone N, Rogers SO, Bandyk DF, Clowes AW, Moneta GL, Lipsitz S, Conte MS. Circulation. 2009; 119: 123–130. Vasc Med. Nov 2009;14(4):397–399 Kreatsoulas C, Anand SS. Disparity in outcomes of surgical revascularization for limb salvage. Race and gender are synergistic determinants of vein graft failure and limb loss. Nguyen LL, Hevelone N, Rogers SO, Bandyk DF, Clowes AW, Moneta GL, Lipsitz S, Conte MS. Circulation. 2009; 119: 123–130. Vasc Med. Nov 2009;14(4):397–399
5.
go back to reference Lam BL, Lee DJ, Zheng DD, Davila EP, Christ SL, Arheart KL. Disparity in prevalence of self-reported visual impairment in older adults among U.S. race-ethnic subgroups. Ophthalmic Epidemiol. 2009;16(3):144–50.PubMedCrossRef Lam BL, Lee DJ, Zheng DD, Davila EP, Christ SL, Arheart KL. Disparity in prevalence of self-reported visual impairment in older adults among U.S. race-ethnic subgroups. Ophthalmic Epidemiol. 2009;16(3):144–50.PubMedCrossRef
6.
go back to reference Tomson CR, Foley RN, Li Q, Gilbertson DT, Xue JL, Collins AJ. Race and end-stage renal disease in the United States Medicare population: the disparity persists. Nephrology (Carlton). 2008;13(7):651–6.CrossRef Tomson CR, Foley RN, Li Q, Gilbertson DT, Xue JL, Collins AJ. Race and end-stage renal disease in the United States Medicare population: the disparity persists. Nephrology (Carlton). 2008;13(7):651–6.CrossRef
7.
go back to reference Hlaing WM. Race/ethnic disparity in hypertension-related hospitalization in Florida. Ethn Dis. 2007;17(3):453–60.PubMed Hlaing WM. Race/ethnic disparity in hypertension-related hospitalization in Florida. Ethn Dis. 2007;17(3):453–60.PubMed
8.
go back to reference Chang KJ, Parasher G, Christie C, Largent J, Anton-Culver H. Risk of pancreatic adenocarcinoma: disparity between African Americans and other race/ethnic groups. Cancer 2005;103(2):349–57. Chang KJ, Parasher G, Christie C, Largent J, Anton-Culver H. Risk of pancreatic adenocarcinoma: disparity between African Americans and other race/ethnic groups. Cancer 2005;103(2):349–57.
9.
go back to reference Hawker GA. The quest for explanations for race/ethnic disparity in rates of use of total joint arthroplasty. J Rheumatol. 2004;31(9):1683–5.PubMed Hawker GA. The quest for explanations for race/ethnic disparity in rates of use of total joint arthroplasty. J Rheumatol. 2004;31(9):1683–5.PubMed
10.
go back to reference Wenger NS, Pearson ML, Desmond KA, et al. Epidemiology of do-not-resuscitate orders. Disparity by age, diagnosis, gender, race, and functional impairment. Arch Intern Med. 1995;155(19):2056–62.PubMedCrossRef Wenger NS, Pearson ML, Desmond KA, et al. Epidemiology of do-not-resuscitate orders. Disparity by age, diagnosis, gender, race, and functional impairment. Arch Intern Med. 1995;155(19):2056–62.PubMedCrossRef
11.
go back to reference Cox ED, Nackers KA, Young HN, Moreno MA, Levy JF, Mangione-Smith RM. Influence of race and socioeconomic status on engagement in pediatric primary care. Patient Educ Couns. 2012;87(3):319–26.PubMedCrossRef Cox ED, Nackers KA, Young HN, Moreno MA, Levy JF, Mangione-Smith RM. Influence of race and socioeconomic status on engagement in pediatric primary care. Patient Educ Couns. 2012;87(3):319–26.PubMedCrossRef
12.
go back to reference Yao L, Robert SA. Examining the racial crossover in mortality between African American and White Older adults: a multilevel survival analysis of race, individual socioeconomic status, and neighborhood socioeconomic context. J Aging Res. 2011;2011:132073.PubMed Yao L, Robert SA. Examining the racial crossover in mortality between African American and White Older adults: a multilevel survival analysis of race, individual socioeconomic status, and neighborhood socioeconomic context. J Aging Res. 2011;2011:132073.PubMed
13.
go back to reference Chu DI, Moreira DM, Gerber L, et al. Effect of race and socioeconomic status on surgical margins and biochemical outcomes in an equal-access health care setting: Results from the Shared Equal Access Regional Cancer Hospital (SEARCH) database. Cancer. Mar 13 2012 Chu DI, Moreira DM, Gerber L, et al. Effect of race and socioeconomic status on surgical margins and biochemical outcomes in an equal-access health care setting: Results from the Shared Equal Access Regional Cancer Hospital (SEARCH) database. Cancer. Mar 13 2012
14.
go back to reference Trinh QD, Sun M, Sammon J, et al. Disparities in access to care at high-volume institutions for uro-oncologic procedures. Cancer. Feb 1 2012 Trinh QD, Sun M, Sammon J, et al. Disparities in access to care at high-volume institutions for uro-oncologic procedures. Cancer. Feb 1 2012
15.
go back to reference FitzGerald JD, Soohoo NF, Losina E, Katz JN. Potential impact on patient residence to hospital travel distance and access to care under a policy of preferential referral to high-volume knee replacement hospitals. Arthritis Care Res. 2012;64(6):890–7.CrossRef FitzGerald JD, Soohoo NF, Losina E, Katz JN. Potential impact on patient residence to hospital travel distance and access to care under a policy of preferential referral to high-volume knee replacement hospitals. Arthritis Care Res. 2012;64(6):890–7.CrossRef
16.
go back to reference Langford AT, Resnicow K, Roberts JS, Zikmund-Fisher BJ. Racial and ethnic differences in direct-to-consumer genetic tests awareness in HINTS 2007: sociodemographic and numeracy correlates. J Genet Couns. 2012;21(3):440–7.PubMedCrossRef Langford AT, Resnicow K, Roberts JS, Zikmund-Fisher BJ. Racial and ethnic differences in direct-to-consumer genetic tests awareness in HINTS 2007: sociodemographic and numeracy correlates. J Genet Couns. 2012;21(3):440–7.PubMedCrossRef
17.
go back to reference Cene CW, Roter D, Carson KA, Miller 3rd ER, Cooper LA. The effect of patient race and blood pressure control on patient–physician communication. J Gen Intern Med. 2009;24(9):1057–64.PubMedCrossRef Cene CW, Roter D, Carson KA, Miller 3rd ER, Cooper LA. The effect of patient race and blood pressure control on patient–physician communication. J Gen Intern Med. 2009;24(9):1057–64.PubMedCrossRef
18.
go back to reference Gordon HS, Street Jr RL, Kelly PA, Souchek J, Wray NP. Physician–patient communication following invasive procedures: an analysis of post-angiogram consultations. Soc Sci Med. 2005;61(5):1015–25.PubMedCrossRef Gordon HS, Street Jr RL, Kelly PA, Souchek J, Wray NP. Physician–patient communication following invasive procedures: an analysis of post-angiogram consultations. Soc Sci Med. 2005;61(5):1015–25.PubMedCrossRef
19.
go back to reference Johnson RL, Roter D, Powe NR, Cooper LA. Patient race and/or ethnicity and quality of patient–physician communication during medical visits. Am J Public Health. 2004;94(12):2084–90.PubMedCrossRef Johnson RL, Roter D, Powe NR, Cooper LA. Patient race and/or ethnicity and quality of patient–physician communication during medical visits. Am J Public Health. 2004;94(12):2084–90.PubMedCrossRef
20.
go back to reference Manfredi C, Kaiser K, Matthews AK, Johnson TP. Are racial differences in patient–physician cancer communication and information explained by background, predisposing, and enabling factors? J Heal Commun. 2010;15(3):272–92.CrossRef Manfredi C, Kaiser K, Matthews AK, Johnson TP. Are racial differences in patient–physician cancer communication and information explained by background, predisposing, and enabling factors? J Heal Commun. 2010;15(3):272–92.CrossRef
21.
go back to reference Jeon-Slaughter H. Economic factors in of patients’ nonadherence to antidepressant treatment. Soc Psychiatry Psychiatr Epidemiol. Mar 14 2012 Jeon-Slaughter H. Economic factors in of patients’ nonadherence to antidepressant treatment. Soc Psychiatry Psychiatr Epidemiol. Mar 14 2012
22.
go back to reference Byrne MM, Souchek J, Richardson M, Suarez-Almazor M. Racial and/or ethnic differences in preferences for total knee replacement surgery. J Clin Epidemiol. 2006;59(10):1078–86.PubMedCrossRef Byrne MM, Souchek J, Richardson M, Suarez-Almazor M. Racial and/or ethnic differences in preferences for total knee replacement surgery. J Clin Epidemiol. 2006;59(10):1078–86.PubMedCrossRef
23.
go back to reference Rosen AB, Tsai JS, Downs SM. Variations in risk attitude across race, gender, and education. Med Dec Making Int J Soc Med Dec Making. 2003;23(6):511–7.CrossRef Rosen AB, Tsai JS, Downs SM. Variations in risk attitude across race, gender, and education. Med Dec Making Int J Soc Med Dec Making. 2003;23(6):511–7.CrossRef
24.
go back to reference Ibrahim SA, Siminoff LA, Burant CJ, Kwoh CK. Differences in expectations of outcome mediate African American/white patient differences in “willingness” to consider joint replacement. Arthritis Rheum. 2002;46(9):2429–35.PubMedCrossRef Ibrahim SA, Siminoff LA, Burant CJ, Kwoh CK. Differences in expectations of outcome mediate African American/white patient differences in “willingness” to consider joint replacement. Arthritis Rheum. 2002;46(9):2429–35.PubMedCrossRef
25.
go back to reference Hofmann JC, Wenger NS, Davis RB, et al. Patient preferences for communication with physicians about end-of-life decisions. SUPPORT Investigators. Study to understand prognoses and preference for outcomes and risks of treatment. Ann Intern Med. 1997;127(1):1–12.PubMed Hofmann JC, Wenger NS, Davis RB, et al. Patient preferences for communication with physicians about end-of-life decisions. SUPPORT Investigators. Study to understand prognoses and preference for outcomes and risks of treatment. Ann Intern Med. 1997;127(1):1–12.PubMed
26.
go back to reference Whittle J, Conigliaro J, Good CB, Lofgren RP. Racial differences in the use of invasive cardiovascular procedures in the Department of Veterans Affairs medical system. N Engl J Med. 1993;329(9):621–7.PubMedCrossRef Whittle J, Conigliaro J, Good CB, Lofgren RP. Racial differences in the use of invasive cardiovascular procedures in the Department of Veterans Affairs medical system. N Engl J Med. 1993;329(9):621–7.PubMedCrossRef
27.
go back to reference Constantinescu F, Goucher S, Weinstein A, Fraenkel L. Racial disparities in treatment preferences for rheumatoid arthritis. Med Care. 2009;47(3):350–5.PubMedCrossRef Constantinescu F, Goucher S, Weinstein A, Fraenkel L. Racial disparities in treatment preferences for rheumatoid arthritis. Med Care. 2009;47(3):350–5.PubMedCrossRef
28.
go back to reference Unequal Treatment: Confronting Racial and Ethnic Disparities in Health Care (full printed version). Committee on Understanding and Eliminating Racial and Ethnic Disparities in Health Care. ISBN: 0-309-50911-4, 782 pages, 6 × 9, (2003). http://www.nap.edu/catalog/10260.html. 2003 Unequal Treatment: Confronting Racial and Ethnic Disparities in Health Care (full printed version). Committee on Understanding and Eliminating Racial and Ethnic Disparities in Health Care. ISBN: 0-309-50911-4, 782 pages, 6 × 9, (2003). http://​www.​nap.​edu/​catalog/​10260.​html. 2003
29.
go back to reference Nelson A. Unequal treatment: confronting racial and ethnic disparities in health care. J Natl Med Assoc. 2002;94(8):666–8.PubMed Nelson A. Unequal treatment: confronting racial and ethnic disparities in health care. J Natl Med Assoc. 2002;94(8):666–8.PubMed
30.
go back to reference Nelson AR. Unequal treatment: report of the Institute of Medicine on racial and ethnic disparities in healthcare. Ann Thorac Surg. 2003;76(4):S1377–1381.PubMedCrossRef Nelson AR. Unequal treatment: report of the Institute of Medicine on racial and ethnic disparities in healthcare. Ann Thorac Surg. 2003;76(4):S1377–1381.PubMedCrossRef
32.
go back to reference Cartwright-Smith L, Rosenbaum S, Mehta D. Disparities Reduction and Minority Health Improvement under the ACA. Vol 3. Washington, D.C.: The George Washington University School of Public Health and Health Services; 2011:1–6 Cartwright-Smith L, Rosenbaum S, Mehta D. Disparities Reduction and Minority Health Improvement under the ACA. Vol 3. Washington, D.C.: The George Washington University School of Public Health and Health Services; 2011:1–6
34.
go back to reference Birnie D, Tung S, Simpson C, et al. Complications associated with defibrillation threshold testing: the Canadian experience. Heart Rhythm Off J Heart Rhythm Soc. 2008;5(3):387–90.CrossRef Birnie D, Tung S, Simpson C, et al. Complications associated with defibrillation threshold testing: the Canadian experience. Heart Rhythm Off J Heart Rhythm Soc. 2008;5(3):387–90.CrossRef
35.
go back to reference Curtis LH, Al-Khatib SM, Shea AM, Hammill BG, Hernandez AF, Schulman KA. Sex differences in the use of implantable cardioverter-defibrillators for primary and secondary prevention of sudden cardiac death. JAMA. 2007;298(13):1517–24.PubMedCrossRef Curtis LH, Al-Khatib SM, Shea AM, Hammill BG, Hernandez AF, Schulman KA. Sex differences in the use of implantable cardioverter-defibrillators for primary and secondary prevention of sudden cardiac death. JAMA. 2007;298(13):1517–24.PubMedCrossRef
36.
go back to reference Hernandez AF, Fonarow GC, Liang L, et al. Sex and racial differences in the use of implantable cardioverter-defibrillators among patients hospitalized with heart failure. JAMA. 2007;298(13):1525–32.PubMedCrossRef Hernandez AF, Fonarow GC, Liang L, et al. Sex and racial differences in the use of implantable cardioverter-defibrillators among patients hospitalized with heart failure. JAMA. 2007;298(13):1525–32.PubMedCrossRef
37.
go back to reference Kaul P, Chang WC, Westerhout CM, Graham MM, Armstrong PW. Differences in admission rates and outcomes between men and women presenting to emergency departments with coronary syndromes. CMAJ. 2007;177(10):1193–9.PubMedCrossRef Kaul P, Chang WC, Westerhout CM, Graham MM, Armstrong PW. Differences in admission rates and outcomes between men and women presenting to emergency departments with coronary syndromes. CMAJ. 2007;177(10):1193–9.PubMedCrossRef
38.
go back to reference Bierman AS, Pugh MJ, Dhalla I, et al. Sex differences in inappropriate prescribing among elderly veterans. Am J Geriatr Pharmacother. 2007;5(2):147–61.PubMedCrossRef Bierman AS, Pugh MJ, Dhalla I, et al. Sex differences in inappropriate prescribing among elderly veterans. Am J Geriatr Pharmacother. 2007;5(2):147–61.PubMedCrossRef
41.
go back to reference •• Zhu Y, Pandya BJ, Choi HK. Prevalence of gout and hyperuricemia in the US general population: the National Health and Nutrition Examination Survey 2007–2008. Arthritis Rheum. 2011;63(10):3136–41. This is the first comprehensive population-based epidemiological study of the prevalence of gout in the US general population.PubMedCrossRef •• Zhu Y, Pandya BJ, Choi HK. Prevalence of gout and hyperuricemia in the US general population: the National Health and Nutrition Examination Survey 2007–2008. Arthritis Rheum. 2011;63(10):3136–41. This is the first comprehensive population-based epidemiological study of the prevalence of gout in the US general population.PubMedCrossRef
42.
go back to reference Helmick CG, Felson DT, Lawrence RC, et al. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I. Arthritis Rheum Jan. 2008;58(1):15–25.CrossRef Helmick CG, Felson DT, Lawrence RC, et al. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I. Arthritis Rheum Jan. 2008;58(1):15–25.CrossRef
43.
go back to reference Singh JA, Strand V. Gout is associated with more comorbidities, poorer health-related quality of life and higher healthcare utilisation in US veterans. Ann Rheum Dis. 2008;67(9):1310–6.PubMedCrossRef Singh JA, Strand V. Gout is associated with more comorbidities, poorer health-related quality of life and higher healthcare utilisation in US veterans. Ann Rheum Dis. 2008;67(9):1310–6.PubMedCrossRef
44.
go back to reference Edwards NL, Sundy JS, Forsythe A, Blume S, Pan F, Becker MA. Work productivity loss due to flares in patients with chronic gout refractory to conventional therapy. J Med Econ. 2011;14(1):10–5.PubMedCrossRef Edwards NL, Sundy JS, Forsythe A, Blume S, Pan F, Becker MA. Work productivity loss due to flares in patients with chronic gout refractory to conventional therapy. J Med Econ. 2011;14(1):10–5.PubMedCrossRef
45.
go back to reference Kleinman NL, Brook RA, Patel PA, et al. The impact of gout on work absence and productivity. Value Health. 2007;10(4):231–7.PubMedCrossRef Kleinman NL, Brook RA, Patel PA, et al. The impact of gout on work absence and productivity. Value Health. 2007;10(4):231–7.PubMedCrossRef
46.
go back to reference Roddy E, Zhang W, Doherty M. Is gout associated with reduced quality of life? A case–control study. Rheumatology (Oxford). 2007;46(9):1441–4.CrossRef Roddy E, Zhang W, Doherty M. Is gout associated with reduced quality of life? A case–control study. Rheumatology (Oxford). 2007;46(9):1441–4.CrossRef
47.
go back to reference Khanna D, Ahmed M, Yontz D, et al. The disutility of chronic gout. Qual Life Res. 2008;17(5):815–22.PubMedCrossRef Khanna D, Ahmed M, Yontz D, et al. The disutility of chronic gout. Qual Life Res. 2008;17(5):815–22.PubMedCrossRef
48.
go back to reference Krishnan E, Baker JF, Furst DE, Schumacher HR. Gout and the risk of acute myocardial infarction. Arthritis Rheum. 2006;54(8):2688–96.PubMedCrossRef Krishnan E, Baker JF, Furst DE, Schumacher HR. Gout and the risk of acute myocardial infarction. Arthritis Rheum. 2006;54(8):2688–96.PubMedCrossRef
49.
go back to reference •• De Vera MA, Rahman MM, Bhole V, Kopec JA, Choi HK. Independent impact of gout on the risk of acute myocardial infarction among elderly women: a population-based study. Ann Rheum Dis. 2010;69(6):1162–4. This is a high-quality cohort study assessing gout as a risk factor for cardiac outcomes.PubMedCrossRef •• De Vera MA, Rahman MM, Bhole V, Kopec JA, Choi HK. Independent impact of gout on the risk of acute myocardial infarction among elderly women: a population-based study. Ann Rheum Dis. 2010;69(6):1162–4. This is a high-quality cohort study assessing gout as a risk factor for cardiac outcomes.PubMedCrossRef
50.
go back to reference Krishnan E, Svendsen K, Neaton JD, Grandits G, Kuller LH, Group MR. Long-term cardiovascular mortality among middle-aged men with gout. Arch Intern Med. 2008;168(10):1104–10.PubMedCrossRef Krishnan E, Svendsen K, Neaton JD, Grandits G, Kuller LH, Group MR. Long-term cardiovascular mortality among middle-aged men with gout. Arch Intern Med. 2008;168(10):1104–10.PubMedCrossRef
51.
go back to reference •• Krishnan E. Gout and the risk for incident heart failure and systolic dysfunction. BMJ Open. 2012;2(1):e000282. This high-quality cohort study established a link between gout and heart failure.PubMedCrossRef •• Krishnan E. Gout and the risk for incident heart failure and systolic dysfunction. BMJ Open. 2012;2(1):e000282. This high-quality cohort study established a link between gout and heart failure.PubMedCrossRef
52.
go back to reference Cohen SD, Kimmel PL, Neff R, Agodoa L, Abbott KC. Association of incident gout and mortality in dialysis patients. J Am Soc Nephrol. 2008;19(11):2204–10.PubMedCrossRef Cohen SD, Kimmel PL, Neff R, Agodoa L, Abbott KC. Association of incident gout and mortality in dialysis patients. J Am Soc Nephrol. 2008;19(11):2204–10.PubMedCrossRef
53.
go back to reference • Charles BA, Shriner D, Doumatey A, et al. A genome-wide association study of serum uric acid in African Americans. BMC Med Genomics. 2011;4:17. This study highlights the genetic correlates of serum uric acid in minorities.PubMedCrossRef • Charles BA, Shriner D, Doumatey A, et al. A genome-wide association study of serum uric acid in African Americans. BMC Med Genomics. 2011;4:17. This study highlights the genetic correlates of serum uric acid in minorities.PubMedCrossRef
54.
go back to reference Rule AD, de Andrade M, Matsumoto M, Mosley TH, Kardia S, Turner ST. Association between SLC2A9 transporter gene variants and uric acid phenotypes in African American and white families. Rheumatology (Oxford). 2011;50(5):871–8.CrossRef Rule AD, de Andrade M, Matsumoto M, Mosley TH, Kardia S, Turner ST. Association between SLC2A9 transporter gene variants and uric acid phenotypes in African American and white families. Rheumatology (Oxford). 2011;50(5):871–8.CrossRef
55.
go back to reference Hochberg MC, Thomas J, Thomas DJ, Mead L, Levine DM, Klag MJ. Racial differences in the incidence of gout. The role of hypertension. Arthritis Rheum. 1995;38(5):628–32.PubMedCrossRef Hochberg MC, Thomas J, Thomas DJ, Mead L, Levine DM, Klag MJ. Racial differences in the incidence of gout. The role of hypertension. Arthritis Rheum. 1995;38(5):628–32.PubMedCrossRef
56.
go back to reference Maynard JW, McAdams Demarco MA, Baer AN, et al. Incident Gout in Women and Association with Obesity in the Atherosclerosis Risk in Communities (ARIC) study. Am J Med. 2012;125(7):717 e719–7.CrossRef Maynard JW, McAdams Demarco MA, Baer AN, et al. Incident Gout in Women and Association with Obesity in the Atherosclerosis Risk in Communities (ARIC) study. Am J Med. 2012;125(7):717 e719–7.CrossRef
57.
go back to reference Portis AJ, Laliberte M, Tatman P, et al. High prevalence of gouty arthritis among the Hmong population in Minnesota. Arthritis Care Res (Hoboken). 2010;62(10):1386–91.CrossRef Portis AJ, Laliberte M, Tatman P, et al. High prevalence of gouty arthritis among the Hmong population in Minnesota. Arthritis Care Res (Hoboken). 2010;62(10):1386–91.CrossRef
58.
go back to reference Wahedduddin S, Singh JA, Culhane-Pera KA, Gertner E. Gout in the Hmong in the United States. J Clin Rheumatol. 2010;16(6):262–6.PubMedCrossRef Wahedduddin S, Singh JA, Culhane-Pera KA, Gertner E. Gout in the Hmong in the United States. J Clin Rheumatol. 2010;16(6):262–6.PubMedCrossRef
60.
go back to reference Stanhope JM, Prior IA. Uric acid, joint morbidity, and streptococcal antibodies in Maori and European teenagers. Rotorua Lakes study 3. Ann Rheum Dis. 1975;34(4):359–63.PubMedCrossRef Stanhope JM, Prior IA. Uric acid, joint morbidity, and streptococcal antibodies in Maori and European teenagers. Rotorua Lakes study 3. Ann Rheum Dis. 1975;34(4):359–63.PubMedCrossRef
61.
go back to reference •• Juraschek SP, Miller 3rd ER, Gelber AC. Body mass index, obesity, and prevalent gout in the United States in 1988–1994 and 2007–2010: body mass index, obesity, and gout. Arthritis Care Res (Hoboken). 2012. This study used NHANES data and described the association between obesity and prevalent gout over time. •• Juraschek SP, Miller 3rd ER, Gelber AC. Body mass index, obesity, and prevalent gout in the United States in 1988–1994 and 2007–2010: body mass index, obesity, and gout. Arthritis Care Res (Hoboken). 2012. This study used NHANES data and described the association between obesity and prevalent gout over time.
62.
go back to reference Phipps-Green AJ, Hollis-Moffatt JE, Dalbeth N, et al. A strong role for the ABCG2 gene in susceptibility to gout in New Zealand Pacific Island and Caucasian, but not Maori, case and control sample sets. Hum Mol Genet. 2010;19(24):4813–9.PubMedCrossRef Phipps-Green AJ, Hollis-Moffatt JE, Dalbeth N, et al. A strong role for the ABCG2 gene in susceptibility to gout in New Zealand Pacific Island and Caucasian, but not Maori, case and control sample sets. Hum Mol Genet. 2010;19(24):4813–9.PubMedCrossRef
63.
go back to reference Hall AP, Barry PE, Dawber TR, McNamara PM. Epidemiology of gout and hyperuricemia. A long-term population study. Am J Med Jan. 1967;42(1):27–37.CrossRef Hall AP, Barry PE, Dawber TR, McNamara PM. Epidemiology of gout and hyperuricemia. A long-term population study. Am J Med Jan. 1967;42(1):27–37.CrossRef
64.
go back to reference Arromdee E, Michet CJ, Crowson CS, O’Fallon WM, Gabriel SE. Epidemiology of gout: is the incidence rising? J Rheumatol. 2002;29(11):2403–6.PubMed Arromdee E, Michet CJ, Crowson CS, O’Fallon WM, Gabriel SE. Epidemiology of gout: is the incidence rising? J Rheumatol. 2002;29(11):2403–6.PubMed
65.
go back to reference Currie WJ. Prevalence and incidence of the diagnosis of gout in Great Britain. Ann Rheum Dis. 1979;38(2):101–6.PubMedCrossRef Currie WJ. Prevalence and incidence of the diagnosis of gout in Great Britain. Ann Rheum Dis. 1979;38(2):101–6.PubMedCrossRef
66.
go back to reference Harris CM, Lloyd DC, Lewis J. The prevalence and prophylaxis of gout in England. J Clin Epidemiol. 1995;48(9):1153–8.PubMedCrossRef Harris CM, Lloyd DC, Lewis J. The prevalence and prophylaxis of gout in England. J Clin Epidemiol. 1995;48(9):1153–8.PubMedCrossRef
67.
go back to reference Grodzicki T, Palmer A, Bulpitt CJ. Incidence of diabetes and gout in hypertensive patients during 8 years of follow-up. The General Practice Hypertension Study Group. J Hum Hypertens Sep. 1997;11(9):583–5.CrossRef Grodzicki T, Palmer A, Bulpitt CJ. Incidence of diabetes and gout in hypertensive patients during 8 years of follow-up. The General Practice Hypertension Study Group. J Hum Hypertens Sep. 1997;11(9):583–5.CrossRef
68.
go back to reference De Souza AW, Fernandes V, Ferrari AJ. Female gout: clinical and laboratory features. J Rheumatol. 2005;32(11):2186–8.PubMed De Souza AW, Fernandes V, Ferrari AJ. Female gout: clinical and laboratory features. J Rheumatol. 2005;32(11):2186–8.PubMed
69.
go back to reference Akizuki S. A population study of hyperuricaemia and gout in Japan—analysis of sex, age and occupational differences in thirty-four thousand people living in Nagano Prefecture. Ryumachi [Rheumatism]. 1982;22(3):201–8. Akizuki S. A population study of hyperuricaemia and gout in Japan—analysis of sex, age and occupational differences in thirty-four thousand people living in Nagano Prefecture. Ryumachi [Rheumatism]. 1982;22(3):201–8.
70.
go back to reference Chen JH, Yeh WT, Chuang SY, Wu YY, Pan WH. Gender-specific risk factors for incident gout: a prospective cohort study. Clin Rheumatol. 2012;31(2):239–45.PubMedCrossRef Chen JH, Yeh WT, Chuang SY, Wu YY, Pan WH. Gender-specific risk factors for incident gout: a prospective cohort study. Clin Rheumatol. 2012;31(2):239–45.PubMedCrossRef
71.
go back to reference Kolz M, Johnson T, Sanna S, et al. Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet Jun. 2009;5(6):e1000504.CrossRef Kolz M, Johnson T, Sanna S, et al. Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet Jun. 2009;5(6):e1000504.CrossRef
72.
go back to reference Kang HR, Jee YK, Kim YS, et al. Positive and negative associations of HLA class I alleles with allopurinol-induced SCARs in Koreans. Pharmacogenet Genomics. 2011;21(5):303–7.PubMedCrossRef Kang HR, Jee YK, Kim YS, et al. Positive and negative associations of HLA class I alleles with allopurinol-induced SCARs in Koreans. Pharmacogenet Genomics. 2011;21(5):303–7.PubMedCrossRef
73.
go back to reference Wells AF, MacDonald PA, Chefo S, Jackson RL. African American patients with gout: efficacy and safety of febuxostat vs allopurinol. BMC Musculoskelet Disord. 2012;13:15.PubMedCrossRef Wells AF, MacDonald PA, Chefo S, Jackson RL. African American patients with gout: efficacy and safety of febuxostat vs allopurinol. BMC Musculoskelet Disord. 2012;13:15.PubMedCrossRef
74.
go back to reference Khosravan R, Kukulka MJ, Wu JT, Joseph-Ridge N, Vernillet L. The effect of age and gender on pharmacokinetics, pharmacodynamics, and safety of febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase. J Clin Pharmacol. 2008;48(9):1014–24.PubMedCrossRef Khosravan R, Kukulka MJ, Wu JT, Joseph-Ridge N, Vernillet L. The effect of age and gender on pharmacokinetics, pharmacodynamics, and safety of febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase. J Clin Pharmacol. 2008;48(9):1014–24.PubMedCrossRef
75.
go back to reference Singh JA, Hodges JS, Toscano JP, Asch SM. Quality of care for gout in the US needs improvement. Arthritis Rheum. 2007;57(5):822–9.PubMedCrossRef Singh JA, Hodges JS, Toscano JP, Asch SM. Quality of care for gout in the US needs improvement. Arthritis Rheum. 2007;57(5):822–9.PubMedCrossRef
76.
go back to reference Krishnan E, Lienesch D, Kwoh CK. Gout in ambulatory care settings in the United States. J Rheumatol. 2008;35(3):498–501.PubMed Krishnan E, Lienesch D, Kwoh CK. Gout in ambulatory care settings in the United States. J Rheumatol. 2008;35(3):498–501.PubMed
77.
go back to reference Solomon DH, Avorn J, Levin R, Brookhart MA. Uric acid lowering therapy: prescribing patterns in a large cohort of older adults. Ann Rheum Dis. 2008;67(5):609–13.PubMedCrossRef Solomon DH, Avorn J, Levin R, Brookhart MA. Uric acid lowering therapy: prescribing patterns in a large cohort of older adults. Ann Rheum Dis. 2008;67(5):609–13.PubMedCrossRef
78.
go back to reference Harrold LR, Yood RA, Mikuls TR, et al. Sex differences in gout epidemiology: evaluation and treatment. Ann Rheum Dis. 2006;65(10):1368–72.PubMedCrossRef Harrold LR, Yood RA, Mikuls TR, et al. Sex differences in gout epidemiology: evaluation and treatment. Ann Rheum Dis. 2006;65(10):1368–72.PubMedCrossRef
79.
go back to reference Singh JA. Can racial disparities in optimal gout treatment be reduced? Evidence from a randomized trial. BMC Med. 2012;10:15.PubMedCrossRef Singh JA. Can racial disparities in optimal gout treatment be reduced? Evidence from a randomized trial. BMC Med. 2012;10:15.PubMedCrossRef
Metadata
Title
Racial and Gender Disparities Among Patients with Gout
Author
Jasvinder A. Singh
Publication date
01-02-2013
Publisher
Current Science Inc.
Published in
Current Rheumatology Reports / Issue 2/2013
Print ISSN: 1523-3774
Electronic ISSN: 1534-6307
DOI
https://doi.org/10.1007/s11926-012-0307-x

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