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01-06-2010

The Impact of Depression in Heart Disease

Authors: Yelizaveta Sher, Sermsak Lolak, José R. Maldonado

Published in: Current Psychiatry Reports | Issue 3/2010

Abstract

Depression and heart disease affect millions of people worldwide. Studies have shown that depression is a significant risk factor for new heart disease and that it increases morbidity and mortality in established heart disease. Many hypothesized and studied mechanisms have linked depression and heart disease, including serotonergic pathway and platelet dysfunction, inflammation, autonomic nervous system and hypothalamic-pituitary-adrenal axis imbalance, and psychosocial factors. Although the treatment of depression in cardiac patients has been shown to be safe and modestly efficacious, it has yet to translate into reduced cardiovascular morbidity and mortality. Understanding the impact and mechanisms behind the association of depression and heart disease may allow for the development of treatments aimed at altering the devastating consequences caused by these comorbid illnesses.

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Title: The Impact of Depression in Heart Disease
Authors: Yelizaveta Sher
Sermsak Lolak
José R. Maldonado
Publication date: 01-06-2010
Publisher: Current Science Inc.
Published in: Current Psychiatry Reports / Issue 3/2010
Print ISSN: 1523-3812
Electronic ISSN: 1535-1645
DOI: https://doi.org/10.1007/s11920-010-0116-8

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

The Impact of Depression in Heart Disease

Abstract

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

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