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Current Osteoporosis Reports
Published in: Current Osteoporosis Reports 3/2013

01-09-2013 | Nutrition and Lifestyle in Osteoporosis (S Ferrari, Section Editor)

Polyunsaturated Fatty Acids and Their Relation with Bone and Muscle Health in Adults

Authors: Kelsey M. Mangano, Shivani Sahni, Jane E. Kerstetter, Anne M. Kenny, Marian T. Hannan

Published in: Current Osteoporosis Reports | Issue 3/2013

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Abstract

Age-related bone and muscle loss are major public health problems. Investigational therapies to reduce these losses include anti-inflammatory dietary supplementations, such as polyunsaturated fatty acids (PUFA). Surprisingly, this topic has received little attention in the osteoporosis community. Recent research highlights the role of PUFA in inflammatory regulation of bone remodeling via cellular pathways. Emerging research suggests significant roles for PUFA in reducing bone and muscle loss with aging; however, findings are conflicted for PUFA and fracture risk. Limited studies suggest a relation between higher omega-3 FA and better muscle/bone in older adults. This review highlights new research since 2008 and synthesizes our current understanding of PUFA in relation to bone and muscle. Across study designs, evidence indicates that PUFA has positive effects upon bone. As data are sparse, future clinical trials and prospective studies are important to determine the long term benefits of PUFA supplementation upon bone and muscle outcomes.
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Metadata
Title
Polyunsaturated Fatty Acids and Their Relation with Bone and Muscle Health in Adults
Authors
Kelsey M. Mangano
Shivani Sahni
Jane E. Kerstetter
Anne M. Kenny
Marian T. Hannan
Publication date
01-09-2013
Publisher
Springer US
Published in
Current Osteoporosis Reports / Issue 3/2013
Print ISSN: 1544-1873
Electronic ISSN: 1544-2241
DOI
https://doi.org/10.1007/s11914-013-0149-0

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