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Published in: Current Oncology Reports 4/2015

01-04-2015 | Gastrointestinal Cancers (B Czito, Section Editor)

Adjuvant and Neoadjuvant Options in Resectable Gastric Cancer: Is There an Optimal Treatment Approach?

Authors: Xuguang Chen, Jennifer R. Eads, John B. Ammori, Aryavarta M. Kumar, Tithi Biswas, Jennifer A. Dorth

Published in: Current Oncology Reports | Issue 4/2015

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Abstract

Gastric cancer is one of the most prevalent and deadliest forms of cancer worldwide. Even though neoadjuvant, perioperative, and adjuvant chemotherapy and/or radiation therapy may improve outcomes compared with surgery alone, the optimal combination of treatment modalities remains controversial. While European and North American trials established perioperative chemotherapy and adjuvant chemoradiation regimens for gastric cancer, Asian countries have focused on the use of adjuvant chemotherapy. This review summarizes results from contemporary randomized controlled trials and meta-analyses to elucidate the relative merits of each treatment approach.
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Metadata
Title
Adjuvant and Neoadjuvant Options in Resectable Gastric Cancer: Is There an Optimal Treatment Approach?
Authors
Xuguang Chen
Jennifer R. Eads
John B. Ammori
Aryavarta M. Kumar
Tithi Biswas
Jennifer A. Dorth
Publication date
01-04-2015
Publisher
Springer US
Published in
Current Oncology Reports / Issue 4/2015
Print ISSN: 1523-3790
Electronic ISSN: 1534-6269
DOI
https://doi.org/10.1007/s11912-015-0442-4

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