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Current Oncology Reports
Published in: Current Oncology Reports 4/2015

01-04-2015 | Gynecologic Cancers (NS Reed, Section Editor)

Radical Surgery in Ovarian Cancer

Authors: Deepa Maheswari Narasimhulu, Fady Khoury-Collado, Dennis S. Chi

Published in: Current Oncology Reports | Issue 4/2015

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Abstract

While there is an ongoing debate regarding the timing of the maximal surgical effort in epithelial ovarian cancer, it is well established that patients with suboptimal tumor debulking derive no benefit from the surgical procedure. The amount of residual disease after cytoreductive surgery has been repeatedly identified as a strong predictor of survival, and accordingly, the surgical effort to achieve the goal of complete gross tumor resection has been constantly evolving. Centers that have adopted the concept of radical surgery in patients with advanced ovarian cancer have reported improvements in their patients’ survival. In addition to the expected improvements in the pharmacologic treatment of this disease, some of the next challenges in the surgical management of ovarian cancer include the preoperative prediction of suboptimal debulking, improving the drug delivery to the tumor, and increasing access to centers of excellence in ovarian cancer regardless of geographical, financial, or other social barriers. This review will discuss an update on the role of surgery in the treatment of primary epithelial ovarian cancer as it has evolved since the emergence of the concept of surgical cytoreduction.
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Metadata
Title
Radical Surgery in Ovarian Cancer
Authors
Deepa Maheswari Narasimhulu
Fady Khoury-Collado
Dennis S. Chi
Publication date
01-04-2015
Publisher
Springer US
Published in
Current Oncology Reports / Issue 4/2015
Print ISSN: 1523-3790
Electronic ISSN: 1534-6269
DOI
https://doi.org/10.1007/s11912-015-0439-z

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