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Current Neurology and Neuroscience Reports

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Open Access 06-10-2022 | Torticollis Spasticus | Dementia (K.S. Marder, Section Editor)

Cognitive and Neuropsychiatric Impairment in Dystonia

Authors: Grace A. Bailey, Eva Martin, Kathryn J. Peall

Published in: Current Neurology and Neuroscience Reports | Issue 11/2022

Abstract

Purpose of Review

To review recent literature evaluating psychiatric and cognitive symptoms in dystonia, the two non-motor symptom groups most frequently evaluated in dystonia research and recognised in clinical practice.

Recent Findings

Recent work has embedded clinical recognition of psychiatric symptoms in dystonia, with depressive and anxiety-related symptoms routinely observed to be the most common. Less explored symptoms, such as self-harm, suicidal ideation, and substance abuse, represent newer areas of investigation, with initial work suggesting higher rates than the background population. Investigation of cognitive function has provided less consistent results, both within individual dystonia subtypes and across the spectrum of dystonias, partly reflecting the heterogeneity in approaches to assessment. However, recent work indicates impairments of higher cognitive function, e.g. social cognition, and disrupted visual and auditory sensory processing.

Summary

Dystonia demonstrates psychiatric and cognitive symptom heterogeneity, with further work needed to recognise endophenotypes and improve diagnostic accuracy, symptom recognition, and management.

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Title: Cognitive and Neuropsychiatric Impairment in Dystonia
Authors: Grace A. Bailey
Eva Martin
Kathryn J. Peall
Publication date: 06-10-2022
Publisher: Springer US
Keywords: Torticollis Spasticus
Dystonia
Anxiety
Published in: Current Neurology and Neuroscience Reports / Issue 11/2022
Print ISSN: 1528-4042
Electronic ISSN: 1534-6293
DOI: https://doi.org/10.1007/s11910-022-01233-3

At a glance: The STEP trials

Springer Medicine

Cognitive and Neuropsychiatric Impairment in Dystonia

Abstract

Purpose of Review

Recent Findings

Summary

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose of Review

Recent Findings

Summary

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