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Current Neurology and Neuroscience Reports
Published in: Current Neurology and Neuroscience Reports 10/2022

21-10-2022 | Multiple Sclerosis | Demyelinating Disorders (L. Wooliscroft and D. Bourdette, Section Editors)

An Update on Diagnostic Laboratory Biomarkers for Multiple Sclerosis

Authors: Marwa Kaisey, Ghazal Lashgari, Justyna Fert-Bober, Daniel Ontaneda, Andrew J. Solomon, Nancy L. Sicotte

Published in: Current Neurology and Neuroscience Reports | Issue 10/2022

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Abstract

Purpose

For many patients, the multiple sclerosis (MS) diagnostic process can be lengthy, costly, and fraught with error. Recent research aims to address the unmet need for an accurate and simple diagnostic process through discovery of novel diagnostic biomarkers. This review summarizes recent studies on MS diagnostic fluid biomarkers, with a focus on blood biomarkers, and includes discussion of technical limitations and practical applicability.

Recent Findings

This line of research is in its early days. Accurate and easily obtainable biomarkers for MS have not yet been identified and validated, but several approaches to uncover them are underway.

Summary

Continue efforts to define laboratory diagnostic biomarkers are likely to play an increasingly important role in defining MS at the earliest stages, leading to better long-term clinical outcomes.
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Metadata
Title
An Update on Diagnostic Laboratory Biomarkers for Multiple Sclerosis
Authors
Marwa Kaisey
Ghazal Lashgari
Justyna Fert-Bober
Daniel Ontaneda
Andrew J. Solomon
Nancy L. Sicotte
Publication date
21-10-2022
Publisher
Springer US
Published in
Current Neurology and Neuroscience Reports / Issue 10/2022
Print ISSN: 1528-4042
Electronic ISSN: 1534-6293
DOI
https://doi.org/10.1007/s11910-022-01227-1

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