Published in:
Open Access 01-09-2019 | Magnetic Resonance Imaging | Neuroimaging (N. Pavese, Section Editor)
Brain Imaging and Impulse Control Disorders in Parkinson’s Disease
Published in: Current Neurology and Neuroscience Reports | Issue 9/2019
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Purpose of Review
Parkinson’s disease (PD) has a wide spectrum of symptoms including the presence of psychiatric disease. At present, most treatment plans, comprised of dopaminergic drugs, are chronic and complex. Though dopaminergic agents are quite efficient in managing the motor aspects of the disease, chronic pharmacotherapy specifically with dopamine receptor agonists has been highly linked to the occurrence of Impulse Compulsive disorder (ICD), which can be problematic for individual patients.
Recent Findings
Much of what is known today about PD-related ICD stems from brain imaging studies, however, evidence is not quite conclusive. Research in the field has been focused on identifying the underlying mechanisms of PD-related ICD and understanding the functions of the structures involved in the reward network.
Summary
This article presents an update of recent findings from key neuroimaging studies in PD-related ICD, discusses results from controversial studies, and identifies areas for future research in the field.