Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Current Infectious Disease Reports
Published in: Current Infectious Disease Reports 11/2016

01-11-2016 | Central Nervous System Infections (K Bloch, Section Editor)

Ocular Syphilis: a Clinical Review

Authors: Sophie L. Woolston, Shireesha Dhanireddy, Jeanne Marrazzo

Published in: Current Infectious Disease Reports | Issue 11/2016

Login to get access

Abstract

While ocular syphilis is not a new phenomenon, recent increased rates of new diagnoses, especially in human immunodeficiency virus (HIV)-infected persons and men who have sex with men, have sparked a new interest in an old disease. This article will review the clinical presentation, diagnosis, and treatment of ocular syphilis, and provide guidance on management.
Literature
1.
(CDC) CfDCaP. Sexually transmitted disease surveillance, 2014. Atlanta: US Department of Health and Human Services; 2015.
2.
3.
4.
5.•
Marra CM, Maxwell CL, Smith SL, et al. Cerebrospinal fluid abnormalities in patients with syphilis: association with clinical and laboratory features. J Infect Dis 2004;189:369–76. Epub 2004 Jan 27. Cerebrospinal fluid of patients with syphilis is a highly nuance, complex subject. This paper provides a review and guide for providers
6.
Balba GP, Kumar PN, James AN, et al. Ocular syphilis in HIV-positive patients receiving highly active antiretroviral therapy. Am J Med. 2006;119:448.e21–5.CrossRef
7.
Ormerod LD, Puklin JE, Sobel JD. Syphilitic posterior uveitis: correlative findings and significance. Clin Infect Dis. 2001;32(12):1661–73.
8.
9.
Gass JD, Braunstein RA, Chenoweth RG. Acute syphilitic posterior placoid chorioretinitis. Ophthalmology. 1990;97:1288–97.CrossRefPubMed
10.
11.•
Amaratunge BC, Camuglia JE, Hall AJ. Syphilitic uveitis: a review of clinical manifestations and treatment outcomes of syphilitic uveitis in human immunodeficiency virus-positive and negative patients. Clin Experiment Ophthalmol. 2010;38:68–74. doi:10.​1111/​j.​442-9071.​2010.​02203.​x. This paper is a well written resource for providers treating ocular syphilis, particularly patients infected with Human Immunodeficiency Virus.CrossRefPubMed
12.
13.
14.
15.
Spoor TC, Ramocki JM, Nesi FA, Sorscher M. Ocular syphilis 1986. Prevalence of FTA-ABS reactivity and cerebrospinal fluid findings. J Clin Neuroophthalmol. 1987;7:191–5.PubMed
16.
Ormerod LD, Puklin JE, Sobel JD. Syphilitic posterior uveitis: correlative findings and significance. Clin Infect Dis. 2001;32:1661–73. Epub 2001 May 21.CrossRefPubMed
17.
Parc CE, Chahed S, Patel SV, Salmon-Ceron D. Manifestations and treatment of ocular syphilis during an epidemic in France. Sex Transm Dis. 2007;34:553–6.CrossRefPubMed
18.
McLeish WM, Pulido JS, Holland S, Culbertson WW, Winward K. The ocular manifestations of syphilis in the human immunodeficiency virus type 1-infected host. Ophthalmology. 1990;97:196–203.CrossRefPubMed
19.
Tran TH, Cassoux N, Bodaghi B, Fardeau C, Caumes E, Lehoang P. Syphilitic uveitis in patients infected with human immunodeficiency virus. Graefes Arch Clin Exp Ophthalmol. 2005;243:863–9. Epub 2005 Mar 15.CrossRefPubMed
20.
21.
22.
Fathilah J, Choo MM. The Jarisch-Herxheimer reaction in ocular syphilis. Med J Malaysia. 2003;58:437–9.PubMed
23.••
Centers for Disease Control and Prevention. Sexually Transmitted Diseases Treatment Guidelines, 2015. MMWR 2015;64. This is an essential text for any provider treating sexually transmitted diseases. It provides a guide for treatment of most syndromes, including very complex cases
24.
Metadata
Title
Ocular Syphilis: a Clinical Review
Authors
Sophie L. Woolston
Shireesha Dhanireddy
Jeanne Marrazzo
Publication date
01-11-2016
Publisher
Springer US
Published in
Current Infectious Disease Reports / Issue 11/2016
Print ISSN: 1523-3847
Electronic ISSN: 1534-3146
DOI
https://doi.org/10.1007/s11908-016-0542-9

Other articles of this Issue 11/2016

Current Infectious Disease Reports 11/2016 Go to the issue

Central Nervous System Infections (K Bloch, Section Editor)

Central Nervous System Device Infections

Sepsis and ICU (JL Vincent, Section Editor)

Understanding Long-Term Outcomes Following Sepsis: Implications and Challenges

Central Nervous System Infections (K Bloch, Section Editor)

Laboratory Diagnosis of Central Nervous System Infection

Central Nervous System Infections (K Bloch, Section Editor)

Human Rabies: a 2016 Update

Central Nervous System Infections (K Bloch, Section Editor)

Progressive Multifocal Leukoencephalopathy in HIV-Uninfected Individuals
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Pediatric Cardiology Video

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

Cardiopulmonary Comorbidity Video

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Valvular Heart Disease Video

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits