Published in:
01-06-2015 | Central Nervous System Infections (J Lyons, Section Editor)
HIV-associated Neurocognitive Disorders and Antiretroviral Therapy: Current Concepts and Controversies
Authors:
Mark R. Etherton, Jennifer L. Lyons, Kevin L. Ard
Published in:
Current Infectious Disease Reports
|
Issue 6/2015
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Abstract
Antiretroviral drugs may help prevent neurological decline in individuals with HIV infection by suppressing viral replication and associated chronic immune activation in the central nervous system. However, HIV control in the brain may come at the price of drug-induced neurotoxicity. Herein, we review recent advances in the balance between adequate viral suppression in the nervous system and adverse effects of the medications used in HIV treatment.